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Combined Stimulation of STN and SNr for Resistant Freezing of Gait in Parkinson's Disease

University Hospital Tuebingen · 2015
ClinicalTrials.gov · Datasets · License: Public Domain · 2015
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deep-brain-stimulationnaparkinson-s-diseasesubthalamic-nucleus
54 patients with idiopathic Parkinson's disease and freezing of gait resistant to subthalamic nucleus stimulation and dopaminergic medication will be included into this multicentre randomised controlled double-blinded parallel group clinical trial. The treatment consists of two different stimulation settings using (i) conventional stimulation of the subthalamic nucleus \[standard STN\] as active comparator and (ii) combined stimulation of active electrode contacts located in both the subthalamic nucleus and substantia nigra pars reticulata \[STN+SNr\].
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