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ErbB2 Positive Metastatic Breast Cancer
Objectives: Phase I part * Primary Objective: To determine the recommended dose of the combination of lapatinib with Lipo-Dox as first line chemotherapy in patients with ErbB2 positive metastatic breast cancer. * Secondary Objectives:To define the safety profile; To observe the response rate and progression free survival Phase II part * Primary Objective :To determined the objective response rate of the combination of lapatinib with Lipo-Dox as first line chemotherapy in patients with ErbB2 positive metastatic breast cancer. * Secondary Objectives:To define the safety profile; To determined the progression free survival
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