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Multi-Agent Retrieval-Augmented Causality Assessment (MARCA) of Individual Case Safety Reports in Pharmacovigilance
Introduction: Increasing volumes of individual case safety reports (ICSRs) challenge expert-led causality assessment in pharmacovigilance. We developed MARCA (Multi-Agent Retrieval-Augmented Causality Assessment), a four-agent framework for Naranjo-based assessment, and evaluated agreement with huma
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