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Mechanistic Insights into Nicotinamidase by Co<sup>II</sup> EPR Spectroscopy

Isabella E. Acosta (26275394) et al. · figshare
Figshare · Datasets · License: CC BY-NC 4.0
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biochemistrybiophysicscomputational-biologyinfectious-diseasesmolecular-biology
Nicotinamidases catalyze the metal-dependent hydrolysis of nicotinamide in the NAD+ salvage pathway in most nonmammalian organisms. Their essential role in pathogenic bacteria, but not mammals, has made them an attractive target for new antibiotic treatments. Most of the characterized nic
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