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Cognitive Fraility and Biomarkers in Older Patients
this study aimed to investigate the association between cognitive fraility and selected plasma and cerebrospinal fluid biomarkers related to neurodegenetaion and neuroinflammation in older adult patients undergoing elective orthopedic surgery. The main questions it aims to answer is: * Can biomarkers indicating neurodegeneration and neuroinflammation be correlated with preoperative frailty and cognitive functions? * Can these biomarkers be used as potential tools for early identification in vulnarable populations?
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