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Alteration of empathy-related behaviors in two strains of mice expressing mutations of the α5 cholinergic nicotinic receptor subunit

Tochon L et al.
Europe PMC · Papers
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A single nucleotide polymorphism (SNP) of the alpha5 subunit of nicotinic acetylcholine receptors (nAChRs) increases human risk for nicotine dependence, alcohol use disorders (AUDs), and schizophrenia. Here, we used transgenic mice carrying either this SNP (rs16969968; α5SNP/α5KI) or a Chrna5 knocko
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