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Two-component system VraSR senses host defense peptide PMAP-36 to promote Streptococcus suis pathogenicity through regulating accD expression

Yandi Pan et al.
HAL (France) · Papers
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medical-and-health-sciencesmedical-microbiologyvirulence
AbstractStreptococcus suis (S. suis) is an important zoonotic pathogen that causes severe infections in humans and animals worldwide. Upon infection, the host innate immune system produces host defense peptides (HDPs) to resist S. suis invasion. PMAP-36, a porcine-derived HDP, has been shown to fail
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