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The Impact of Exercise on Subthalamic Nucleus Neural Activity in Parkinson's Disease

Jay Alberts · 2023
ClinicalTrials.gov · Datasets · License: Public Domain · 2023
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deep-brain-stimulationnaparkinson-disease
Fifteen PwPD who have undergone DBS surgery and utilize the Percept system will complete a FE and VE exercise session on a stationary cycle while Off antiparkinsonian medication. Bilateral neural activity of the STN will be continuously recorded for 130 minutes (pre-, during FE or VE and post-exercise). The Movement Disorders Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) III Motor Exam and upper extremity force-tracking task will be used to determine motor response to exercise.
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