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From Trait-Structured Within-Host Dynamics to SIR Models: A Multiscale Framework With Re-Exposure

Cyrille Kenne et al.
HAL (France) · Papers
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Abstract We present a threshold-based multiscale framework that links mechanistic within-host infection dynamics to a structured, SIR-like population model. Starting from a two-variable system for pathogen load and immune response that includes inoculum (Allee-like) thresholds and nonlinear immune a
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