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Sulfonylurea Bioisosteres of Sulfonic Acid in JFD 00458‐Based ST6GAL1 Inhibitors Enhance Membrane Permeability

Natan Koraj et al.
HAL (France) · Papers
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Sialyltransferases catalyze the transfer of sialic acid to glycoconjugates within the Golgi apparatus, generating cell‐surface sialoglycans that regulate cell–cell and immune communication. This process can be modulated by inhibiting α−2,6‐sialyltransferase 1 (ST6GAL1), one of the most important sia
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