bioRxiv / medRxiv
open access
Lymphatic Spread Patterns in HPV+ vs. HPV- Oropharyngeal Squamous Cell Carcinoma: A Multi-Center European Analysis
BackgroundHuman papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC) shows higher prevalence of lymph node metastases than HPV-negative OPSCC. It remains unclear whether HPV-positive and HPV-negative OPSCC differ in occult metastasis risk, which is relevant to personalize elec
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