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Study of Tegavivint Plus Zanzalintinib in Patients With Advanced Hepatocellular Carcinoma

University of Texas Southwestern Medical Center · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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hepatocellular-carcinoma-hcc
The goal of this clinical trial is to evaluate the combination of zanzalintinib (XL092) and tegavivint in advanced hepatocellular carcinoma (HCC) and Wnt pathway mutations who have progressed after at least one prior line of systemic therapy and are naïve (not previously treated with) standard of care tyrosine kinase inhibitors targeting vascular endothelial growth factor signaling.
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