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The Effect of GLP-1 Receptor Activation on Central Reward and Satiety in Obesity and Diabetes

Amsterdam UMC, location VUmc · 2011
ClinicalTrials.gov · Datasets · License: Public Domain · 2011
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diabetes-mellitusnaobesityrewardtype-2type-2-diabetes-mellitus
Glucagon-like peptide 1 (GLP-1) based therapies, such as exenatide, are already successfully employed in the treatment of Type 2 Diabetes (T2DM). Exenatide improves glycemic control and is associated with reduced food intake and body weight. The investigators hypothesize that it affects central reward and satiety circuits and that this may contribute to the weight loss.
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