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Skeletal effects of JAK1/2 inhibition versus IL-6 receptor blockade in rheumatoid arthritis: a post hoc comparative cohort analysis based on two prospective observational studies
Introduction: Janus kinase inhibitors (JAKi) are increasingly used in rheumatoid arthritis (RA), yet comparative data on systemic effects beyond joint inflammation remain limited. Because chronic inflammation promotes generalized bone loss and IL-6-driven osteoclastogenesis, we compared the skeletal
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