bioRxiv / medRxiv
open access
Development and validation of early warning scores predicting 24-hour mortality addressing intercurrent medical interventions: a multi-centre retrospective cohort study of 2,08 million hospital encounters
BackgroundThe National Early Warning Score (NEWS) is widely used to predict patient deterioration, but retrospective validations face intervention bias and emphasise discrimination over clinical utility. We aimed to compare NEWSs clinical net benefit against simplified scoring rules and machine lear
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