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The cardiac myosin binding protein-C-myosin S2 interaction: modulation of cardiac contractility and its role in hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a common inherited cardiac disorder caused primarily by pathogenic variants in sarcomeric genes encoding β-cardiac myosin heavy chain (MYH7) and cardiac myosin binding protein-C (MYBPC3; cMyBP-C). cMyBP-C plays a central role in the modulation of co
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