Europe PMC
open access
Diphenhydramine disrupts sleep architecture in 5XFAD Alzheimer's disease model and wild-type mice
Sleep disruption is common in Alzheimer's disease (AD). Diphenhydramine (DPH), a first-generation antihistamine with anticholinergic properties, is widely used as an over-the-counter sleep aid. We tested whether chronic DPH treatment alters sleep architecture in 5XFAD and wild-type female mice. Fema
Conceptio Open Archive
Analyze & explore related research in Conceptio
Connect this record directly into your research workflow or AI agent. Explore citations across open repositories, query full text, and export structured proof bundles.
This document is indexed with metadata only: full text is not available in the archive for this record. Open the official source ↗
Related documents
- Modafinil's Effects on Cognition in Remitted MDD#1213067
- SAR231893-LPS15497- "Dupilumab Effect on Sleep in AD Patients"#891753
- A Study to Assess the Effect of Upadacitinib in Atopic Dermatitis-induced Sleep Disturbance in Adults With Moderate to Severe Atopic Dermatitis#1351267
- Napping, Sleep, Cognitive Decline and Risk of Alzheimer's Disease#902885
- Altered behavioral characteristics of sleep-wake cycle and histaminergic systems in histamine H<SUB>1</SUB> receptor knockout mice#70225
Record · ID 1500354
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Bring this data into your agent: Connect via MCP or API · 20 free credits to start · no card required
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive