HAL (France)
open access
Linking germline telomere removal to global programmed DNA elimination in Tetrahymena genome differentiation
In the ciliate Tetrahymena , telomeres of the germline micronucleus (MIC) are removed and replaced by de novo telomere addition during somatic macronuclear (MAC) development. In this study, we investigated the kinetics and mechanism of the MIC telomere elimination. Comparison of the MIC and MAC geno
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