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SR-A1 cooperates with TLR4-NF-κB signaling to drive macrophage TGF-β1 expression and Treg induction during schistosome infection
Helminths induce regulatory T cells (Tregs) to establish chronic infections, promoting long-term persistence of both parasites and hosts. TGF-β1 is essential for Treg induction by initiating Foxp3 expression. Helminth infections are typically associated with high TGF-β1 levels, yet the mechanisms b
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