HAL (France)
open access
PCSK9 as a mediator of monocytes transendothelial activation in obstructive sleep apnoea: A translational study
Obstructive sleep apnoea (OSA) causes intermittent hypoxia (IH) during sleep which is the main trigger for associated cardiovascular complications. IH increases endothelial permeability and vascular remodelling. The proprotein convertase subtilisine kexine type 9 (PCSK9) is capable of promoting vasc
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