Medical Technologies. Pharmaceutical Cosmetology, Cosmeceuticals Based on Herbal Medicines: Modern Trends and Regulatory Approaches

Medical Technologies. Pharmaceutical Cosmetology, Cosmeceuticals Based on Herbal Medicines: Modern Trends and Regulatory Approaches | Zenodo Skip to main Communities My dashboard Log in Sign up Zenodo is currently experiencing slowness and intermittent outages due to heavy automated traffic from bots and AI crawlers. We are aware of the problem, and our team is focused on stabilizing the service. Thank you for your patience. Published May 3, 2026 | Version v1 Journal article Open Medical Technologies. Pharmaceutical Cosmetology, Cosmeceuticals Based on Herbal Medicines: Modern Trends and Regulatory Approaches Authors/Creators Osyntseva, Alina Shapovalov, Valerii Shapovalov, Valentyn Description Introduction. Modern cosmetology is characterized by the integration of medical technologies, pharmaceutical and cosmetic approaches, which led to the formation of cosmeceuticals as a separate direction. A special place in cosmeceuticals is occupied by phytopreparations that contain biologically active substances (flavonoids, carotenoids, triterpenoids) and provide a complex effect on the skin. Purpose of the study. To analyze the role of herbal remedies in cosmeceuticals on the example of Calendula officinalis L. (calendula extract), to conduct a comparative analysis with the requirements of Deutsches Arzneibuch (DAB), as well as to perform a SWOT (Strengths, Weaknesses, Opportunities, Threats)- and PESTEL (Political, Economic, Social, Technological, Environmental, Legal) analysis of the development of phytocosmeceuticals. Materials and methods. Documentary analysis of scientific sources and regulatory documentation, comparative analysis of pharmacopoeia requirements, pharmacological analysis of biologically active substances (quercetin, β-carotene, oleanolic acid derivatives), as well as SWOT and PESTEL analysis were used. Cosmeceutical preparations, in particular Calendula ointment (International Nonproprietary Name: Calendula extract) and dexpanthenol agents (chemical name: (R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide) were studied. Results. It has been established that herbal remedies provide anti-inflammatory, antiseptic, antioxidant, and regenerative effects due to their multicomponent composition. Calendula extract has been shown to be effective in the treatment of inflammatory and degenerative skin conditions. It has been found that the requirements of DAB are more stringent and provide for standardization according to marker compounds and the use of chromatographic methods (TLC - (Thin-Layer Chromatography), HPLC (High-Performance Liquid Chromatography). SWOT analysis demonstrated the strengths of phytocosmeceuticals (naturalness, biocompatibility) and limitations (composition variability), while PESTEL analysis confirmed the significant impact of macroeconomic and regulatory factors on the development of the industry. Conclusions. Herbal remedies are a promising area of cosmeceuticals that combines effectiveness and safety. Calendula officinalis L. is one of the key ingredients in modern cosmeceuticals. It is necessary to improve the standardization system in accordance with European requirements and introduce innovative technologies to improve the quality of products. Files osintsevaFIN.pdf Files (561.2 kB) Name Size Download all osintsevaFIN.pdf md5:ec2a117040bdc122e851ae9c8b9ce01c 561.2 kB Preview Download Additional details References 1. Shapovalova V., Osyntseva A., Shapovalov V. Medical Technologies: Pharmaceutical Cosmetology, Cosmeceuticals - Opportunities and Limitations. Annals of Mechnikov's Institute. 2026. No.1. 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DOI: https://doi.org/10.30978/TB2026-1-36 52 Views 33 Downloads Show more details All versions This version Views Total views 52 52 Downloads Total downloads 33 33 Data volume Total data volume 20.2 MB 20.2 MB More info on how stats are collected.... Versions External resources Indexed in OpenAIRE Communities Keywords and subjects Keywords cosmeceuticals herbal medicines Calendula officinalis calendula extract flavonoids dexpanthenol pharmacopoeia SWOT analysis PESTEL analysis Details DOI DOI Badge DOI 10.5281/zenodo.20009226 Markdown [](https://doi.org/10.5281/zenodo.20009226) reStructuredText .. image:: https://zenodo.org/badge/DOI/10.5281/zenodo.20009226.svg :target: https://doi.org/10.5281/zenodo.20009226 HTML <a href="https://doi.org/10.5281/zenodo.20009226"><img src="https://zenodo.org/badge/DOI/10.5281/zenodo.20009226.svg" alt="DOI"></a> Image URL https://zenodo.org/badge/DOI/10.5281/zenodo.20009226.svg Target URL https://doi.org/10.5281/zenodo.20009226 Resource type Journal article Publisher Zenodo Published in Annals of Mechnikov Institute, 2, 30-42, ISSN: 1993-4327, 2026. 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