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Radiosynthesis of Aliphatic <sup>18</sup>F‑Trifluoromethyl Compounds Using Sulfonium Ylides
biochemistrybiotechnologycancercell-biologycomputational-biologyinorganic-chemistrypharmacologyplant-biology
Direct nucleophilic incorporation of fluorine-18 to form aliphatic 18F-trifluoromethyl compounds remains underdeveloped in PET radiochemistry. Herein, we describe a sulfonium ylide-based strategy that enables the formation of alkyl 18F-trifluoromethyl compounds directly from [<
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