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References - A psychological talking therapy for suicidality in people experiencing non-affective psychosis: Mechanism and efficacy outcomes of the CARMS (Cognitive AppRoaches to coMbatting Suicidality) randomised controlled trial - NCBI Bookshelf An official website of the United States government Here's how you know The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Log in Show account info Close Account Logged in as: username Dashboard Publications Account settings Log out Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Bookshelf Search database Books All Databases Assembly Biocollections BioProject BioSample Books ClinVar Conserved Domains dbVar Gene Genome GEO DataSets GEO Profiles GTR Identical Protein Groups MedGen MeSH NLM Catalog Nucleotide OMIM PMC Protein Protein Clusters Protein Family Models PubChem BioAssay PubChem Compound PubChem Substance PubMed SNP SRA Structure Taxonomy ToolKit ToolKitAll ToolKitBookgh Search term Search Browse Titles Advanced Help Disclaimer NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. Gooding P, Awenat Y, Drake R, et al. A psychological talking therapy for suicidality in people experiencing non-affective psychosis: Mechanism and efficacy outcomes of the CARMS (Cognitive AppRoaches to coMbatting Suicidality) randomised controlled trial. Southampton (UK): National Institute for Health and Care Research; 2026 Mar. (Efficacy and Mechanism Evaluation, No. 13.03.) A psychological talking therapy for suicidality in people experiencing non-affective psychosis: Mechanism and efficacy outcomes of the CARMS (Cognitive AppRoaches to coMbatting Suicidality) randomised controlled trial. Show details Efficacy and Mechanism Evaluation, No. 13.03. Gooding P, Awenat Y, Drake R, et al. Southampton (UK): National Institute for Health and Care Research ; 2026 Mar. Contents Search term < Prev Next > References 1. Tarrier N, Gooding P, Pratt D, Kelly J, Awenat Y, Maxwell J. Cognitive Behavioural Prevention of Suicide in Psychosis: A Treatment Manual. London, UK: Routledge; 2013. 2. Haddock G, Pratt D, Gooding PA, Peters S, Emsley R, Evans E, et al. Feasibility and acceptability of suicide prevention therapy on acute psychiatric wards: randomised controlled trial. BJPsych Open 2019;5:e14. 10.1192/bjo.2018.85 [ PMC free article : PMC6381415 ] [ PubMed : 30762509 ] [ CrossRef ] 3. Pratt D, Gooding P, Awenat Y, Eccles S, Tarrier N. Cognitive behavioural suicide prevention for male prisoners: case examples. Cogn Behav Pract 2016;23:485–501. [ PMC free article : PMC5047357 ] [ PubMed : 27713616 ] 4. O’Connor RC, Nock MK. The psychology of suicidal behaviour. Lancet Psychiatry 2014;1:73–85. 10.1016/S2215-0366(14)70222-6 [ PubMed : 26360404 ] [ CrossRef ] 5. WHO. Suicide Data. 2020. URL: https://www ​.who.int/data ​/gho/data/themes ​/mental-health/suicide-rates (accessed 2 February 2026). 6. AFSP. Suicide Statistics. 2020. URL: https://afsp ​.org/about-suicide ​/suicide-statistics/ (accessed 9 March 2020). 7. Office for National Statistics. Suicides in the United Kingdom: 2018 Registrations. 2019. URL: www ​.ons.gov.uk/peoplepopulationandcommunity ​/birthsdeathsandmarriages ​/deaths/bulletins ​/suicidesintheunitedkingdom ​/2018registrations (accessed 5 June 2020). 8. Peterson C, Sussell A, Li J, Schumacher PK, Yeoman K, Stone DM. Suicide rates by industry and occupation — National violent death reporting system, 32 states, 2016. MMWR Morb Mortal Wkly Rep 2020;69:57–62. 10.15585/mmwr.mm6903a1 [ PMC free article : PMC7367035 ] [ PubMed : 31971929 ] [ CrossRef ] 9. Samaritans. Suicide Statistics Report. 2019. URL: https://media ​.samaritans ​.org/documents/SamaritansSuicideStatsReport ​_2019_Full_report.pdf (accessed 2 February 2026). 10. GOV.UK. Serlf Harm and Suicidal Thoughts and Attempts. 2019. URL: www ​.ethnicity-facts-figures ​.service.gov.uk ​/health/mental-health ​/adults-reporting-suicidal-thoughts-attempts-and-self-harm/1.5#data-sources (accessed 9 March 2020). 11. NIMH. Suicide. 2019. URL: www ​.nimh.nih.gov/health ​/statistics/suicide.shtml (accessed 9 March 2020). 12. Large M, Corderoy A, McHugh C. Is suicidal behaviour a stronger predictor of later suicide than suicidal ideation? A systematic review and meta-analysis. Aust N Z J Psychiatry 2021;55:254–67. 10.1177/0004867420931161 [ PubMed : 32579030 ] [ CrossRef ] 13. Chapman CL, Mullin K, Ryan CJ, Kuffel A, Nielssen O, Large MM. Meta-analysis of the association between suicidal ideation and later suicide among patients with either a schizophrenia spectrum psychosis or a mood disorder. Acta Psychiatr Scand 2015;131:162–73. 10.1111/acps.12359 [ PubMed : 25358861 ] [ CrossRef ] 14. Correll CU, Solmi M, Croatto G, Schneider LK, Rohani-Montez SC, Fairley L, et al. Mortality in people with schizophrenia: a systematic review and meta-analysis of relative risk and aggravating or attenuating factors. World Psychiatry 2022;21:248–71. 10.1002/wps.20994 [ PMC free article : PMC9077617 ] [ PubMed : 35524619 ] [ CrossRef ] 15. Chesney E, Goodwin GM, Fazel S. Risks of all-cause and suicide mortality in mental disorders: a meta-review. World Psychiatry 2014;13:153–60. 10.1002/wps.20128 [ PMC free article : PMC4102288 ] [ PubMed : 24890068 ] [ CrossRef ] 16. Hawton K, van Heeringen K. Suicide. Lancet 2009;373:1372–81. [ PubMed : 19376453 ] 17. Yates K, Lang U, Cederlof M, Boland F, Taylor P, Cannon M, et al. Association of psychotic experiences with subsequent risk of suicidal ideation, suicide attempts, and suicide deaths a systematic review and meta-analysis of longitudinal population studies. JAMA Psychiatry 2019;76:180–9. 10.1001/jamapsychiatry.2018.3514 [ PMC free article : PMC6439738 ] [ PubMed : 30484818 ] [ CrossRef ] 18. DeVylder JE, Lukens EP, Link BG, Lieberman JA. Suicidal ideation and suicide attempts among adults with psychotic experiences data from the collaborative psychiatric epidemiology surveys. JAMA Psychiatry 2015;72:219–25. 10.1001/jamapsychiatry.2014.2663 [ PubMed : 25715312 ] [ CrossRef ] 19. Saham S, Chant D, McGrath J. A systematic review of mortality in schizophrenia. Arch Gen Psychiatry 2007;64:1123–31. [ PubMed : 17909124 ] 20. Bolton C, Gooding P, Kapur N, Barrowclough C, Tarrier N. Developing psychological perspectives of suicidal behaviour and risk in people with a diagnosis of schizophrenia: we know they kill themselves but do we understand why? Clin Psychol Rev 2007;27:511–36. [ PubMed : 17229508 ] 21. Johnson J, Gooding P, Tarrier N. Suicide risk in schizophrenia: explanatory models and clinical implications, the schematic appraisal model of suicide (SAMS). Psychol Psychother 2008;81:55–77. [ PubMed : 17919360 ] 22. Van Orden KA, Witte TK, Cukrowicz KC, Braithwaite SR, Selby EA, Joiner TE. The interpersonal theory of suicide. Psychol Rev 2010;117:575–600. [ PMC free article : PMC3130348 ] [ PubMed : 20438238 ] 23. O’Connor RC. The integrated motivational-volitional model of suicidal behavior. Crisis 2011;32:295–8. 10.1027/0227-5910/a000120 [ PubMed : 21945841 ] [ CrossRef ] 24. Johnson J, Tarrier N, Gooding P. An investigation of aspects of the cry of pain model of suicide risk: the role of defeat in impairing memory. Behav Res Ther 2008;46:968–75. 10.1016/j.brat.2008.04.007 [ PubMed : 18514615 ] [ CrossRef ] 25. Gilbert P. Evolutionary approaches to psychopathology: the role of natural defences. Aust N Z J Psychiatry 2001;35:17–27. [ PubMed : 11270452 ] 26. Rasmussen SA, Fraser L, Gotz M, MacHale S, Mackie R, Masterton G, et al. Elaborating the cry of pain model of suicidality: testing a psychological model in a sample of first-time and repeat self-harm patients. Br J Clin Psychol 2010;49:15–30. 10.1348/014466509x415735 [ PubMed : 19302734 ] [ CrossRef ] 27. Stenzel JS, Holler I, Rath D, Hallensleben N, Spangenberg L, Glaesmer H, Forkmann T. Do feelings of defeat and entrapment change over time? an investigation of the integrated motivational-volitional model of suicidal behaviour using ecological momentary assessments. Int J Environ Res Public Health 2020;17:4685. 10.3390/ijerph17134685 [ PMC free article : PMC7369950 ] [ PubMed : 32610667 ] [ CrossRef ] 28. Williams JMG, Crane C, Barnhofer T, Duggan D. Psychology and Suicidal Behaviour: Elaborating the Entrapment Model. Oxford: Oxford University Press; 2005. pp. 71–89. 29. Gilbert P, Allan S. The role of defeat and entrapment (arrested flight) in depression: an exploration of an evolutionary view. Psychol Med 1998;28:585–98. 10.1017/s0033291798006710 [ PubMed : 9626715 ] [ CrossRef ] 30. Birchwood M, Mason R, MacMillan F, Healy J. Depression, demoralisation and control over psychotic illness: a comparison of depressed and non-depressed patients with a chronic psychosis. Psychol Med 1993;23:387–95. 10.1017/S0033291700028488 [ PubMed : 8332655 ] [ CrossRef ] 31. Rooke O, Birchwood M. Loss, humiliation and entrapment as appraisals of schizophrenic illness: a prospective study of depressed and non-depressed patients. Br J Clin Psychol 1998;37:259–68. [ PubMed : 9874588 ] 32. Taylor PJ, Gooding P, Wood AM, Tarrier N. The role of defeat and entrapment in depression, anxiety, and suicide. Psychol Bull 2011;137:391–420. 10.1037/a0022935 [ PubMed : 21443319 ] [ CrossRef ] 33. O’Connor RC, Fraser L, Whyte MC, Machale S, Masterton G. A comparison of specific positive future expectancies and global hopelessness as predictors of suicidal ideation in a prospective study of repeat self-harmers. J Affect Disord 2008;110:207–14. [ PubMed : 18262284 ] 34. Beck AT. Hopelessness as a predictor of eventual suicide. Ann N Y Acad Sci 1986;487:90–6. [ PubMed : 3471167 ] 35. Beck AT, Brown GK, Steer RA, Dahlsgaard KK, Grisham JR. Suicide ideation at its worst point: a predictor of eventual suicide in psychiatric outpatients. Suicide Life Threat Behav 1999;29:1–9. [ PubMed : 10322616 ] 36. Klonsky DE, Kotov R, Bakst S, Rabinowitz J, Bromet EJ. Hopelessness as a predictor of attempted suicide among first admission patients with psychosis: a 10-year cohort study. Suicide Life Threat Behav 2012;42:1–10. 10.1111/j.1943-278X.2011.00066.x [ PMC free article : PMC3330175 ] [ PubMed : 22320192 ] [ CrossRef ] 37. Wolfe KL, Nakonezny PA, Owen VJ, Rial KV, Moorehead AP, Kennard BD, Emslie GJ. Hopelessness as a predictor of suicide ideation in depressed male and female adolescent youth. Suicide Life Threat Behav 2019;49:253–63. 10.1111/sltb.12428 [ PMC free article : PMC6013307 ] [ PubMed : 29267993 ] [ CrossRef ] 38. Caldwell CB, Gottesman II. Schizophrenics kill themselves too – a review of risk-factors for suicide. Schizophr Bull 1990;16:571–89. [ PubMed : 2077636 ] 39. White RG, McCleery M, Gumley AI, Mulholland C. Hopelessness in schizophrenia: the impact of symptoms and beliefs about illness. J Nerv Ment Dis 2007;195:968–75. [ PubMed : 18091189 ] 40. Williams JMG, Van der Does AJW, Barnhofer T, Crane C, Segal ZS. Cognitive reactivity, suicidal ideation and future fluency: preliminary investigation of a differential activation theory of hopelessness/suicidality. Cognit Ther Res 2008;32:83–104. 41. Nordentoft M, Jeppesen P, Abel M, Kassow P, Petersen L, Thorup A, et al. OPUS study: suicidal behaviour, suicidal ideation and hopelessness among patients with first-episode psychosis – one-year follow-up of a randomised controlled trial. Br J Psychiatry 2002;181:s98–s106. [ PubMed : 12271808 ] 42. Tarrier N, Kelly J, Maqsood S, Snelson N, Maxwell J, Law H, et al. The cognitive behavioural prevention of suicide in psychosis: a clinical trial. Schizophr Res 2014;156:204–10. 10.1016/j.schres.2014.04.029 [ PubMed : 24853059 ] [ CrossRef ] 43. Palmier-Claus JE, Taylor PJ, Gooding P, Dunn G, Lewis SW. Affective variability predicts suicidal ideation in individuals at ultra-high risk of developing psychosis: an experience sampling study. Br J Clin Psychol 2012;51:72–83. 10.1111/j.2044-8260.2011.02013.x [ PubMed : 22268542 ] [ CrossRef ] 44. Hutton P, Bowe S, Parker S, Ford S. Prevalence of suicide risk factors in people at ultra-high risk of developing psychosis: a service audit. Early Interv Psychiatry 2011;5:375–80. 10.1111/j.1751-7893.2011.00302.x [ PubMed : 22032551 ] [ CrossRef ] 45. Skodlar B, Tomori M, Parnas J. Subjective experience and suicidal ideation in schizophrenia. Compr Psychiatry 2008;49:482–8. 10.1016/j.comppsych.2008.02.008 [ PubMed : 18702934 ] [ CrossRef ] 46. Gooding P, Haddock G, Harris K, Asriah M, Awenat Y, Cook L, et al. The interplay between suicidal experiences, psychotic experiences and interpersonal relationships: a qualitative study. BMC Psychiatry 2023;23:873. 10.1186/s12888-023-05164-2 [ PMC free article : PMC10668454 ] [ PubMed : 38001403 ] [ CrossRef ] 47. Pollock LR, Williams JMG. Problem-solving in suicide attempters. Psychol Med 2004;34:163–7. [ PubMed : 14971637 ] 48. Grover KE, Green KL, Pettit JW, Monteith LL, Garza MJ, Venta A. Problem solving moderates the effects of life event stress and chronic stress on suicidal behaviors in adolescence. J Clin Psychol 2009;65:1281–90. 10.1002/jclp.20632 [ PubMed : 19827110 ] [ CrossRef ] 49. Panagioti M, Gooding P, Taylor PJ, Tarrier N. Perceived social support buffers the impact of PTSD symptoms on suicidal behavior: implications into suicide resilience research. Compr Psychiatry 2014;55:104–12. 10.1016/j.comppsych.2013.06.004 [ PubMed : 23972619 ] [ CrossRef ] 50. Owen R, Jones SH, Dempsey RC, Gooding PA. Directly or indirectly? the role of social support in the psychological pathways underlying suicidal ideation in people with bipolar disorder. Int J Environ Res Public Health 2022;19:5286. 10.3390/ijerph19095286 [ PMC free article : PMC9099991 ] [ PubMed : 35564679 ] [ CrossRef ] 51. Panagioti M, Gooding PA, Tarrier N. A prospective study of suicidal ideation in posttraumatic stress disorder: the role of perceptions of defeat and entrapment. J Clin Psychol 2015;71:50–61. 10.1002/jclp.22103 [ PubMed : 24913436 ] [ CrossRef ] 52. Tarrier N, Taylor K, Gooding P. Cognitive-behavioral interventions to reduce suicide behavior a systematic review and meta-analysis. Behav Modif 2008;32:77–108. [ PubMed : 18096973 ] 53. Pratt D, Tarrier N, Dunn G, Awenat Y, Shaw J, Ulph F, Gooding P. Cognitive-behavioural suicide prevention for male prisoners: a pilot randomized controlled trial. Psychol Med 2015;45:3441–51. 10.1017/s0033291715001348 [ PMC free article : PMC4682193 ] [ PubMed : 26165919 ] [ CrossRef ] 54. O’Connor RC, Kirtley OJ. The integrated motivational-volitional model of suicidal behaviour. Philos Trans R Soc Lond B Biol Sci 2018;373:20170268. 10.1098/rstb.2017.0268 [ PMC free article : PMC6053985 ] [ PubMed : 30012735 ] [ CrossRef ] 55. O’Connor RC, Portzky G. Looking to the future: a synthesis of new developments and challenges in suicide research and prevention. Front Psychol 2018;9:2139. 10.3389/fpsyg.2018.02139 [ PMC free article : PMC6277491 ] [ PubMed : 30538647 ] [ CrossRef ] 56. Mewton L, Andrews G. Cognitive behavioral therapy for suicidal behaviors: improving patient outcomes. Psychol Res Behav Manag 2016;9:21–9. 10.2147/prbm.s84589 [ PMC free article : PMC4780394 ] [ PubMed : 27042148 ] [ CrossRef ] 57. Donker T, Calear A, Busby Grant J, van Spijker B, Fenton K, Hehir KK, et al. Suicide prevention in schizophrenia spectrum disorders and psychosis: a systematic review. BMC Psychol 2013;1:6. 10.1186/2050-7283-1-6 [ PMC free article : PMC4269996 ] [ PubMed : 25566358 ] [ CrossRef ] 58. Meerwijk EL, Parekh A, Oquendo MA, Allen IE, Franck LS, Lee KA. Direct versus indirect psychosocial and behavioural interventions to prevent suicide and suicide attempts: a systematic review and meta-analysis. Lancet Psychiatry 2016;3:544–54. 10.1016/s2215-0366(16)00064-x [ PubMed : 27017086 ] [ CrossRef ] 59. Wu H, Lu L, Qian Y, Jin XH, Yu HR, Du L, et al. The significance of cognitive-behavioral therapy on suicide: an umbrella review. J Affect Disord 2022;317:142–8. 10.1016/j.jad.2022.08.067 [ PubMed : 36041581 ] [ CrossRef ] 60. Penades R, Forte F, Mezquida G, González-Rodríguez A, García-Rizo C, Catalán R, Bernardo M. Effectiveness of cognitive behavioural therapy for suicide in schizophrenia: a systematic review. Curr Psychiatry Res Rev 2022;18:36–45. 10.2174/2666082218666211220164527 [ CrossRef ] 61. Awenat Y, Shaw-Núñez E, Kelly J, Law H, Ahmed S, Welford M, et al. A qualitative analysis of the experiences of people with psychosis of a novel cognitive behavioural therapy targeting suicidality. Psychosis 2017;9:38–47. 62. Tarrier N, Haddock G, Lewis S, Drake R, Gregg L; SoCRATES Trial Group. Suicide behaviour over 18 months in recent onset schizophrenic patients: the effects of CBT. Schizophr Res 2006;83:15–27. 10.1016/j.schres.2005.12.846 [ PubMed : 16460916 ] [ CrossRef ] 63. Gooding P, Tarrier N, Dunn G, Awenat Y, Shaw J, Ulph F, Pratt D. Psychological characteristics and predictors of suicidal thoughts and behaviours in high risk prisoners. Crim Justice Behav 2017;44:321–35. 64. Pratt D, Gooding P, Kelly J, Johnson J, Tarrier N. Case Formulation in Suicidal Behaviour. In Tarrier N, editor. Case Formulation in Cognitive Behaviour Therapy: The Treatment of Challenging and Complex Cases. London: Routledge; 2015. 65. Gooding PA, Pratt D, Awenat Y, Drake R, Elliott R, Emsley R, et al. A psychological intervention for suicide applied to non-affective psychosis: the CARMS (Cognitive AppRoaches to coMbatting Suicidality) randomised controlled trial protocol. BMC Psychiatry 2020;20:306. 10.1186/s12888-020-02697-8 [ PMC free article : PMC7298803 ] [ PubMed : 32546129 ] [ CrossRef ] 66. Harris K, Gooding P, Haddock G, Peters S. Factors that contribute to psychological resilience to suicidal thoughts and behaviours in people with schizophrenia diagnoses: qualitative study. BJPsych Open 2019;5:e79. 10.1192/bjo.2019.63 [ PMC free article : PMC6737512 ] [ PubMed : 31496458 ] [ CrossRef ] 67. Taylor PJ, Gooding PA, Wood AM, Johnson J, Pratt D, Tarrier N. Defeat and entrapment in schizophrenia: the relationship with suicidal ideation and positive psychotic symptoms. Psychiatry Res 2010;178:244–8. 10.1016/j.psychres.2009.10.015 [ PubMed : 20472304 ] [ CrossRef ] 68. Taylor PJ, Wood AM, Gooding P, Tarrier N. Appraisals and suicidality: the mediating role of defeat and entrapment. Arch Suicide Res 2010;14:236–47. 10.1080/13811118.2010.494138 [ PubMed : 20658377 ] [ CrossRef ] 69. Gooding P, Pratt D, Edwards D, Awenat Y, Drake RJ, Emsley R, et al. Underlying mechanisms and efficacy of a suicide-focused psychological intervention for psychosis, the Cognitive Approaches to Combatting Suicidality (CARMS): a multicentre, assessor-masked, randomised controlled trial in the UK. Lancet Psychiatry 2025;12:177–88. 10.1016/S2215-0366(24)00399-7 [ PubMed : 39827886 ] [ CrossRef ] 70. Hopewell S, Chan AW, Collins GS, Hróbjartsson A, Moher D, Schulz KF, et al. CONSORT 2025 statement: updated guideline for reporting randomised trials. BMJ 2025;389:e081123. 10.1136/bmj-2024-081123 [ PMC free article : PMC11995449 ] [ PubMed : 40228833 ] [ CrossRef ] 71. Chan AW, Boutron I, Hopewell S, Moher D, Schulz KF, Collins GS, et al. SPIRIT 2025 statement: updated guideline for protocols of randomised trials. BMJ 2025;389:e081477. 10.1136/bmj-2024-081477 [ PMC free article : PMC12035670 ] [ PubMed : 40294953 ] [ CrossRef ] 72. Hoffmann TC, Glasziou PP, Boutron I, Milne R, Perera R, Moher D, et al. Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide. BMJ 2014;348:g1687. 10.1136/bmj.g1687 [ PubMed : 24609605 ] [ CrossRef ] 73. World Health Organization. ICD-10: International Statistical Classification of Diseases and Related Health Problems: Tenth Revision. 2nd edn. Geneva: World Health Organization; 2004. 74. Owen R, Gooding P, Dempsey R, Jones S. A qualitative investigation into the relationships between social factors and suicidal thoughts and acts experienced by people with a bipolar disorder diagnosis. J Affect Disord 2015;176:133–40. 10.1016/j.jad.2015.02.002 [ PubMed : 25706607 ] [ CrossRef ] 75. Awenat Y, Peters S, Shaw-Nunez E, Gooding P, Pratt D, Haddock G. Staff experiences and perceptions of working with in-patients who are suicidal: qualitative analysis. Br J Psychiatry 2017;211:103–8. 10.1192/bjp.bp.116.191817 [ PMC free article : PMC5537568 ] [ PubMed : 28642259 ] [ CrossRef ] 76. Gooding PA, Littlewood D, Owen R, Johnson J, Tarrier N. Psychological resilience in people experiencing schizophrenia and suicidal thoughts and behaviours. J Ment Health 2019;28:597–603. 10.1080/09638237.2017.1294742 [ PubMed : 28635432 ] [ CrossRef ] 77. Morse J. Designing Funded Qualitative Research. In Denzin N, Lincoln YS, editors. Handbook of Qualitative Research. 2nd edn. Thousand Oaks, CA: Sage; 1994. pp. 220–35. 78. Mansournia MA, Higgins JP, Sterne JA, Hernán MA. Biases in randomized trials: a conversation between trialists and epidemiologists. Epidemiology 2017;28:54–9. 10.1097/ede.0000000000000564 [ PMC free article : PMC5130591 ] [ PubMed : 27748683 ] [ CrossRef ] 79. Higgins JP, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, et al.; Cochrane Bias Methods Group. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ 2011;343:d5928. 10.1136/bmj.d5928 [ PMC free article : PMC3196245 ] [ PubMed : 22008217 ] [ CrossRef ] 80. Reynolds WM. Adult Suicidal Ideation Questionnaire: Professional Manual. Odessa, FL: Psychological Assessment Resources; 1991. 81. Cull J, Gill W. Suicide Probability Scale (SPS) Manual. Los Angeles, CA: Western Psychological Services; 1988. 82. Beck AT, Steer RA. Manual for Beck Scale for Suicidal Ideation. New York: Psychological Corporation; 1991. 83. Pinninti N, Steer RA, Rissmiller DJ, Nelson S, Beck AT. Use of the Beck Scale for Suicide Ideation with psychiatric inpatients diagnosed with schizophrenia, schizoaffective, or bipolar disorders. Behav Res Ther 2002;40:1071–9. [ PubMed : 12296492 ] 84. Robinson SM, Sobell LC, Sobell MB, Leo GI. Reliability of the timeline followback for cocaine, cannabis, and cigarette use. Psychol Addict Behav 2014;28:154–62. 10.1037/a0030992 [ PubMed : 23276315 ] [ CrossRef ] 85. Sobell LC, Sobell MB. Timeline Follow-back: A Technique for Assessing Self-reported Alcohol Consumption. In Litten RZ, Allen JP, editors. Measuring Alcohol Consumption: Psychosocial and Biochemical Methods. Totawa NJ: Humana Press; 1992. pp. 41–72. 86. Gratz KL, Roemer L. Multidimensional assessment of emotion regulation and dysregulation: development, factor structure, and initial validation of the difficulties in emotion regulation scale. J Psychopathol Behav Assess 2008;30:315. 87. Hallon LS, Steinman SA, Tolin DF, Diefenbach GJ. Psychometric properties of the difficulties in emotion regulation scale (DERS) and its short forms in adults with emotional disorders. Front Psychol 2018;9:539. [ PMC free article : PMC5917244 ] [ PubMed : 29725312 ] 88. D’Zurilla TJ, Nezu AM, Maydeu-Olivares T. Social Problem-Solving Inventory-Revised: Technical Manual. New York: Multi-Health Systems; 2002. 89. Vaux A, Phillips J, Holly L, Thomson B, Williams D, Stewart D. The social support appraisals (SS-A) scale: studies of reliability and validity. Am J Community Psychol 1986;14:195–218. 90. Beck AT, Weissman A, Lester D, Trexler L. The measurement of pessimism: the hopelessness scale. J Consult Clin Psychol 1974;42:861–5. [ PubMed : 4436473 ] 91. Littlewood D, Gooding P, Panagioti M, Kyle SD. Nightmares and suicide in posttraumatic stress disorder: the mediating role of defeat, entrapment and hopelessness. J Clin Sleep Med 2016;12:393–9. [ PMC free article : PMC4773636 ] [ PubMed : 26564386 ] 92. Panagioti M, Gooding PA, Tarrier N. Hopelessness, defeat, and entrapment in posttraumatic stress disorder their association with suicidal behavior and severity of depression. J Nerv Ment Dis 2012;200:676–83. 10.1097/NMD.0b013e3182613f91 [ PubMed : 22850302 ] [ CrossRef ] 93. Kay SR, Fiszbein A, Opler LA. The Positive and negative syndrome scale (PANSS) for Schizophrenia. Schizophr Bull 1987;13:261–76. [ PubMed : 3616518 ] 94. Haddock G, McCarron J, Tarrier N, Faragher EB. Scale to measure dimensions of hallucinations and delusions: the psychotic symptom rating scales (PSYRATS). Psychol Med 1999;29:879–89. [ PubMed : 10473315 ] 95. Morosini PL, Magliano L, Brambilla L, Ugolini S, Pioli R. Development, reliability and acceptability of a new version of the DSM-IV Social and Occupational Functioning Assessment Scale (SOFAS) to assess routine social functioning. Acta Psychiatr Scand 2000;101:323–9. [ PubMed : 10782554 ] 96. Addington D, Addington J, Schissel B. A depression rating scale for schizophrenics. Schizophr Res 1990;3:247–51. [ PubMed : 2278986 ] 97. Day E, Copello A, Hull M. Assessment and management of alcohol use disorders. BMJ 2015;350:h715. 10.1136/bmj.h715 [ PubMed : 25698774 ] [ CrossRef ] 98. Skinner HA. The drug abuse screening test. Addict Behav 1982;7:363–71. 10.1016/0306-4603(82)90005-3 [ PubMed : 7183189 ] [ CrossRef ] 99. Sobell LC, Sobell MB. Timeline Follow-Back. In Litten RZ, Allen JP, editors. Measuring Alcohol Consumption: Psychosocial and Biochemical Methods. Totowa, NJ: Humana Press; 1992. pp. 41–72. 100. Gregg L, Barrowclough C, Haddock G. Development and validation of a scale for assessing reasons for substance use in schizophrenia: the ReSUS scale. Addict Behav 2009;34:830–7. 10.1016/j.addbeh.2009.03.004 [ PubMed : 19339121 ] [ CrossRef ] 101. Espie CA, Kyle SD, Hames P, Gardani M, Fleming L, Cape J. The Sleep Condition Indicator: a clinical screening tool to evaluate insomnia disorder. BMJ Open 2014;4:e004183. 10.1136/bmjopen-2013-004183 [ PMC free article : PMC3964344 ] [ PubMed : 24643168 ] [ CrossRef ] 102. Horowitz M, Wilner N, Alvarez W. Impact of Event Scale: a measure of subjective stress. Psychosom Med 1979;41:209–18. 10.1097/00006842-197905000-00004 [ PubMed : 472086 ] [ CrossRef ] 103. Horvath AO, Greenberg LS. Development and validation of the working alliance inventory. J Couns Psychol 1989;36:223–33. 104. Tarrier N, Haddock G. Cognitive-behavior Therapy for the Treatment of Schizophrenia: A Case Formulation Approach. In Hofman S, Tompson M, editors. Handbook of Psychological Treatments for Severe Mental Disorders. New York: Guilford Press; 2002. 105. Beecham J, Knapp M. Costing Psychiatric Interventions. In Thornicroft, G, editor. Measuring Mental Health Needs. London, UK: Gaskell; 2001. pp. 200–24. 106. Devlin NJ, Shah KK, Feng Y, Mulhern B, van Hout B. Valuing health-related quality of life: an EQ-5D-5L value set for England. Health Econ 2018;27:7–22. 10.1002/hec.3564 [ PMC free article : PMC6680214 ] [ PubMed : 28833869 ] [ CrossRef ] 107. Feng Y, Devlin N, Herdman M. Assessing the health of the general population in England: how do the three- and five-level versions of EQ-5D compare? Health Qual Life Outcomes 2015;13:1–16. 10.1186/s12955-015-0356-8 [ PMC free article : PMC4618130 ] [ PubMed : 26489956 ] [ CrossRef ] 108. Janssen MF, Pickard AS, Golicki D, Gudex C, Niewada M, Scalone L, et al. Measurement properties of the EQ-5D-5L compared to the EQ-5D-3L across eight patient groups: a multi-country study. Qual Life Res 2013;22:1717–27. 10.1007/s11136-012-0322-4 [ PMC free article : PMC3764313 ] [ PubMed : 23184421 ] [ CrossRef ] 109. Golicki D, Niewada M, Buczek J, Karlińska A, Kobayashi A, Janssen MF, Pickard AS. Validity of EQ-5D-5L in stroke. Qual Life Res 2014;24:845–50. 10.1007/s11136-014-0834-1 [ PMC free article : PMC4366565 ] [ PubMed : 25347978 ] [ CrossRef ] 110. Golicki D, Niewada M, Karlinska A, Buczek J, Kobayashi A, Janssen MF, Pickard AS. Comparing responsiveness of the EQ-5D-5L, EQ-5D-3L and EQ VAS in stroke patients. Qual Life Res 2015;24:1555–63. 10.1007/s11136-014-0873-7 [ PMC free article : PMC4457098 ] [ PubMed : 25425288 ] [ CrossRef ] 111. Dudley R, Kuyken W. Case Formulation in Cognitive Behavioural Therapy: A Principle driven approach. In Johnstone L, Dallos R, editors. Formulation in Psychology and Psychotherapy. London and New York: Routledge; 2013. 112. Johnson J, Gooding PA, Wood AM, Tarrier N. Resilience as positive coping appraisals: testing the schematic appraisals model of suicide (SAMS). Behav Res Ther 2010;48:179–86. 10.1016/j.brat.2009.10.007 [ PubMed : 19906364 ] [ CrossRef ] 113. Haddock G, Devane S, Bradshaw T, McGovern J, Tarrier N, Kinderman P, et al. An investigation into the psychometric properties of the cognitive therapy scale for psychosis (CTS-Psy). Behav Cogn Psychother 2001;29:221–33. 10.1017/S1352465801002089 [ CrossRef ] 114. Ioannidis JP, Evans SJ, Gotzsche PC, O'Neill RT, Altman DG, Schulz K, Moher D; for the CONSORT Group. Better reporting of harms in randomized trials: an extension of the CONSORT statement. Ann Intern Med 2004141;141:781–8. [ PubMed : 15545678 ] 115. Peters S, Cook L, Littlewood D, Awenat Y, Drake R, Gill J, et al. A systematic investigation of the short and long term experiences of taking part in research about suicidal thoughts and acts in the context of a randomised control trial. J Soc Sci Med 2022;2:100157. 116. Harris K, Gooding P, Awenat Y, Haddock G, Cook L, Huggett C, et al. Acceptability of a novel suicide prevention psychological therapy for people who experience non-affective psychosis. Psychol Psychother 2023;96:560–76. 10.1111/papt.12456 [ PMC free article : PMC10953419 ] [ PubMed : 36856293 ] [ CrossRef ] 117. Peters S, Awenat AF, Gooding P, Harris K, Cook L, Huggett C, et al. What is important to service users and staff when implementing suicide-focused psychological therapies for people with psychosis into mental health services? Front Psychiatry 2023;14:1154092. 10.3389/fpsyt.2023.1154092 [ PMC free article : PMC10213358 ] [ PubMed : 37252139 ] [ CrossRef ] 118. Peters S. Qualitative research methods in mental health. Evid Based Ment Health 2010;13:35–40. [ PubMed : 21856603 ] 119. Malterud K, Siersma V, Guassora AD. Information Power: Sample Content and Size in Qualitative Studies. In Carmic PM, editor. Qualitative Research in Psychology: Expanding Perspectives in Methodology and Design. Washington: American Psychological Association; 2021. pp. 67–81. 120. Boutron I, Altman DG, Moher D, Schulz KF, Ravaud P; CONSORT NPT Group. CONSORT statement for randomized trials of nonpharmacologic treatments: a 2017 update and a CONSORT extension for nonpharmacologic trial abstracts. Ann Intern Med 2017;167:40–7. 10.7326/m17-0046%m28630973 [ PubMed : 28630973 ] [ CrossRef ] 121. Brown VA. An introduction to linear mixed-effects modeling in R. Adv Methods Pract Psychol Sci 2021;4:2515245920960351. 10.1177/2515245920960351 [ CrossRef ] 122. Kahan BC, Jairath V, Doré CJ, Morris TP. The risks and rewards of covariate adjustment in randomized trials: an assessment of 12 outcomes from 8 studies. Trials 2014;15:139. 10.1186/1745-6215-15-139 [ PMC free article : PMC4022337 ] [ PubMed : 24755011 ] [ CrossRef ] 123. Kahan BC, Rushton H, Morris TP, Daniel RM. A comparison of methods to adjust for continuous covariates in the analysis of randomised trials. BMC Med Res Methodol 2016;16:42. 10.1186/s12874-016-0141-3 [ PMC free article : PMC4827223 ] [ PubMed : 27068456 ] [ CrossRef ] 124. Emsley R, Dunn G, White IR. Mediation and moderation of treatment effects in randomised controlled trials of complex interventions. Stat Methods Med Res 2010;19:237–70. 10.1177/0962280209105014 [ PubMed : 19608601 ] [ CrossRef ] 125. Landau S, Emsley R, Dunn G. Beyond total treatment effects in RCTs: why we need to measure outcomes at baseline when investigating mediation. Trials 2015;16:O42. 10.1186/1745-6215-16-S2-O42 [ CrossRef ] 126. Dunn G, Maracy M, Tomenson BM. Estimating treatment effects from randomized clinical trials with non-compliance and loss to follow-up: the role of instrumental variable methods. Stat Methods Med Res 2005;14:369–95. 10.1191/0962280205sm403oa [ PubMed : 16178138 ] [ CrossRef ] 127. Dunn G, Emsley R, Liu H, Landau S, Green J, White I, Pickles A. Evaluation and validation of social and psychological markers in randomised trials of complex interventions in mental health: a methodological research programme. Health Technol Assess 2015;19:1–116. 10.3310/hta19930 [ PMC free article : PMC4781463 ] [ PubMed : 26560448 ] [ CrossRef ] 128. Ramsey SD, Willke RJ, Glick H, Reed SD, Augustovski F, Jonsson B, et al. Cost-effectiveness analysis alongside clinical trials II-An ISPOR good research practices task force report. Value Health 2015;18:161–72. 10.1016/j.jval.2015.02.001 [ PubMed : 25773551 ] [ CrossRef ] 129. Hernández Alava M, Pudney S, Wailoo A. Estimating the relationship between EQ-5D-5L and EQ-5D-3L: Results from a UK population study. PharmacoEconomics 2023;41:199–207. 10.1007/s40273-022-01218-7 [ PMC free article : PMC9883358 ] [ PubMed : 36449173 ] [ CrossRef ] 130. Linden M. How to define, find and classify side effects in psychotherapy: from unwanted events to adverse treatment reactions. Clin Psychol Psychother 2013;20:286–96. 10.1002/cpp.1765 [ PubMed : 22253218 ] [ CrossRef ] 131. Sekhon M, Cartwright M, Francis JJ. Acceptability of healthcare interventions: an overview of reviews and development of a theoretical framework. BMC Health Serv Res 2017;17:88. 10.1186/s12913-017-2031-8 [ PMC free article : PMC5267473 ] [ PubMed : 28126032 ] [ CrossRef ] 132. Braun V, Clarke V. Using thematic analysis in psychology. Qual Res Psychol 2006;3:77–101. 10.1191/1478088706qp063oa [ CrossRef ] 133. Braun V, Clarke V. Conceptual and design thinking for thematic analysis. Qual Psychol 2022;9:3–26. 10.1037/qup0000196 [ CrossRef ] 134. Littlewood DL, Harris K, Gooding P, Pratt D, Haddock G, Peters S. Using my demons to make good: the short-and long-term impact of participating in suicide-related research. Arch Suicide Res 2021;25:315–39. [ PubMed : 31544686 ] 135. van Ballegooijen W, Littlewood DL, Nielsen E, Kapur N, Gooding P. The temporal relationships between defeat, entrapment and suicidal ideation: ecological momentary assessment study. BJPsych Open 2022;8:e105. 10.1192/bjo.2022.68 [ PMC free article : PMC9230440 ] [ PubMed : 35656578 ] [ CrossRef ] 136. Gysin-Maillart A, Schwab S, Soravia L, Megert M, Michel K. A novel brief therapy for patients who attempt suicide: a 24-months follow-up randomized controlled study of the attempted suicide short intervention program (ASSIP). PLOS Med 2016;13:e1001968. 10.1371/journal.pmed.1001968 [ PMC free article : PMC4773217 ] [ PubMed : 26930055 ] [ CrossRef ] 137. Joiner TE, Van Orden KA, Witte TK, Selby EA, Ribeiro JD, Lewis R, Rudd MD. Main predictions of the interpersonal-psychological theory of suicidal behavior: empirical tests in two samples of young adults. J Abnorm Psychol 2009;118:634–46. [ PMC free article : PMC2846517 ] [ PubMed : 19685959 ] 138. Deas N, Kowalski R, Finnell S, Radovic E, Carroll H, Robbins C, et al. I just want to matter: examining the role of anti-mattering in online suicide support communities using natural language processing. Comput Hum Behav 2023;139:107499. 10.1016/j.chb.2022.107499 [ CrossRef ] 139. Elliott GC, Colangelo ME, Gelles RJ. Mattering and suicide ideation: establishing and elaborating a relationship. Soc Psychol Q 2005;68:223–38. 10.1177/019027250506800303 [ CrossRef ] 140. Flett GL. An introduction, review, and conceptual analysis of mattering as an essential construct and an essential way of life. J Psychoeduc Assess 2022;40:3–36. 10.1177/07342829211057640 [ CrossRef ] 141. Milner A, Page KM, LaMontagne AD. Perception of mattering and suicide ideation in the Australian working population: evidence from a cross-sectional survey. Community Ment Health J 2016;52:615–21. 10.1007/s10597-016-0002-x [ PubMed : 26939798 ] [ CrossRef ] 142. van Wijngaarden E, Leget C, Goossensen A. Ready to give up on life: the lived experience of elderly people who feel life is completed and no longer worth living. Soc Sci Med 2015;138:257–64. 10.1016/j.socscimed.2015.05.015 [ PubMed : 25982088 ] [ CrossRef ] 143. Taylor PJ, Awenat Y, Gooding P, Johnson J, Pratt D, Wood A, Tarrier N. The subjective experience of participation in schizophrenia research a practical and ethical issue. J Nerv Ment Dis 2010;198:343–8. [ PubMed : 20458196 ] 144. Owen R, Gooding P, Dempsey R, Jones S. The experience of participation in suicide research from the perspective of individuals with bipolar disorder. J Nerv Ment Dis 2016;204:840–4. [ PubMed : 26915014 ] 145. Littlewood DL, Harris K, Gooding P, Pratt D, Haddock G, Peters S. Using my demons to make good: the short- and long-term impact of participating in suicide-related research. Arch Suicide Res 2019;25:315–39. 10.1080/13811118.2019.1663330 [ PubMed : 31544686 ] [ CrossRef ] 146. Biddle L, Cooper J, Owen-Smith A, Klineberg E, Bennewith O, Hawton K, et al. Qualitative interviewing with vulnerable populations: individuals’ experiences of participating in suicide and self-harm based research. J Affect Disord 2013;145:356–62. 10.1016/j.jad.2012.08.024 [ PubMed : 23021191 ] [ CrossRef ] 147. Blades CA, Stritzke WGK, Page AC, Brown JD. The benefits and risks of asking research participants about suicide: a meta-analysis of the impact of exposure to suicide-related content. Clin Psychol Rev 2018;64:1–12. 10.1016/j.cpr.2018.07.001 [ PubMed : 30014862 ] [ CrossRef ] 148. Ammerman BA, Carter SP, Gebhardt HM, Buchholz J, Reger MA. An initial investigation of suicide attempt disclosures among US veterans. Crisis 2021;42:411–7. 10.1027/0227-5910/a000727 [ PubMed : 33153300 ] [ CrossRef ] 149. Reger MA, Ammerman BA, Carter SP, Gebhardt HM, Rojas SM, Lee JM, Buchholz J. Patient feedback on the use of predictive analytics for suicide prevention. Psychiatr Serv 2021;72:129–35. 10.1176/appi.ps.202000092 [ PubMed : 33138714 ] [ CrossRef ] 150. Dazzi T, Gribble R, Wessely S, Fear NT. Does asking about suicide and related behaviours induce suicidal ideation? What is the evidence? Psychol Med 2014;44:3361–3. 10.1017/s0033291714001299 [ PubMed : 24998511 ] [ CrossRef ] 151. Deeley ST, Love AW. Does asking adolescents about suicidal ideation induce negative mood state? Violence Vict 2010;25:677–88. 10.1891/0886-6708.25.5.677 [ PubMed : 21061872 ] [ CrossRef ] 152. Morton V, Torgerson DJ. Effect of regression to the mean on decision making in health care. BMJ 2003;326:1083–4. 10.1136/bmj.326.7398.1083 [ PMC free article : PMC1125994 ] [ PubMed : 12750214 ] [ CrossRef ] 153. Lincoln TM, Jung E, Wiesjahn M, Schlier B. What is the minimal dose of cognitive behavior therapy for psychosis? An approximation using repeated assessments over 45 sessions. Eur Psychiatry 2016;38:31–9. 10.1016/j.eurpsy.2016.05.004 [ PubMed : 27642702 ] [ CrossRef ] 154. Spencer HM, McMenamin M, Emsley R, Turkington D, Dunn G, Morrison AP, et al. Cognitive behavioral therapy for antipsychotic-free schizophrenia spectrum disorders: does therapy dose influence outcome? Schizophr Res 2018;202:385–6. 10.1016/j.schres.2018.07.016 [ PubMed : 30017459 ] [ CrossRef ] 155. Freeman D. Developing psychological treatments for psychosis. Br J Psychiatry 2024;224:147–9. 10.1192/bjp.2024.5 [ PMC free article : PMC11039552 ] [ PubMed : 38652062 ] [ CrossRef ] 156. Owen R, Dempsey R, Jones S, Gooding P. Defeat and entrapment in bipolar disorder: exploring the relationship with suicidal ideation from a psychological theoretical perspective. Suicide Life Threat Behav 2018;48:116–28. 10.1111/sltb.12343 [ PubMed : 28276599 ] [ CrossRef ] 157. Owen R, Gooding P, Dempsey R, Jones S. The reciprocal relationships between social factors and the experience of bipolar disorder: a qualitative investigation. Clin Psychol Psychother 2017;24:911–8. [ PubMed : 27862615 ] 158. Panagioti M, Gooding P, Dunn G, Tarrier N. Pathways to suicidal behavior in posttraumatic stress disorder. J Trauma Stress 2011;24:137–45. 10.1002/jts.20627 [ PubMed : 21438017 ] [ CrossRef ] 159. O’Connor RC, Cassidy C. Predicting hopelessness: the interaction between optimism/pessimism and specific future expectancies. Cogn Emot 2007;21:596–613. 160. Zortea TC, Cleare S, Wetherall K, Melson AJ, O’Connor RC. 8.22 - Suicide Risk: From Psychological Processes to Clinical Assessment and Intervention. In Asmundson GJG, editor. Comprehensive Clinical Psychology. 2nd edn. Oxford: Elsevier; 2022. pp. 406–25. 161. Flett G, Khan A, Su C. Mattering and psychological well-being in college and university students: review and recommendations for campus-based initiatives. Int J Ment Health Addict 2019;17:667–80. 10.1007/s11469-019-00073-6 [ CrossRef ] 162. Flett GL. Resilience to Interpersonal Stress: Why Mattering Matters When Building the Foundation of Mentally Healthy Schools. In Leschied AW, Saklofske DH, Flett GL, editors. Handbook of School-Based Mental Health Promotion: An Evidence-Informed Framework for Implementation. Cham, Switzerland: Springer International Publishing; 2018. pp. 383–410. 163. Flett GL, Burdo R, Nepon T. Mattering, insecure attachment, rumination, and self-criticism in distress among university students. Int J Ment Health Addict 2020;19:1300–13. 10.1007/s11469-020-00225-z [ CrossRef ] 164. Flett GL, Heisel MJ. Aging and feeling valued versus expendable during the COVID-19 pandemic and beyond: a review and commentary of why mattering is fundamental to the health and well-being of older adults. Int J Ment Health Addict 2021;19:2443–69. 10.1007/s11469-020-00339-4 [ PMC free article : PMC7295320 ] [ PubMed : 32837430 ] [ CrossRef ] 165. Flett GL, Heisel MJ. Aging and feeling valued versus expendable during the COVID-19 pandemic and beyond: a review and commentary of why mattering is fundamental to the health and well-being of older adults. Int J Ment Health Addict 2021;19:2443–69. 10.1007/s11469-020-00339-4 [ PMC free article : PMC7295320 ] [ PubMed : 32837430 ] [ CrossRef ] 166. Taylor J, McFarland MJ, Carr DC. Age, perceptions of mattering, and allostatic load. J Aging Health 2019;31:1830–49. 10.1177/0898264318795805 [ PubMed : 30182793 ] [ CrossRef ] 167. Flett G. The Psychology of Mattering: Understanding the Human Need to be Significant. London: Academic Press; 2018. 168. Ribeiro JD, Joiner TE. The interpersonal-psychological theory of suicidal behavior: current status and future directions. J Clin Psychol 2009;65:1291–9. [ PubMed : 19827114 ] 169. Chu C, Buchman-Schmitt JM, Stanley IH, Hom MA, Tucker RP, Hagan CR, et al. The interpersonal theory of suicide: a systematic review and meta-analysis of a decade of cross-national research. Psychol Bull 2017;143:1313–45. 10.1037/bul0000123 [ PMC free article : PMC5730496 ] [ PubMed : 29072480 ] [ CrossRef ] 170. Drabenstott M. A matter of life and death: integrating mattering into the interpersonal-psychological theory of suicide. Suicide Life Threat Behav 2019;49:1006–18. 10.1111/sltb.12504 [ PubMed : 30091197 ] [ CrossRef ] 171. Colizzi M, Ruggeri M, Lasalvia A. Should we be concerned about stigma and discrimination in people at risk for psychosis? A systematic review. Psychol Med 2020;50:705–26. 10.1017/s0033291720000148 [ PubMed : 32063250 ] [ CrossRef ] 172. Corrigan PW, Druss BG, Perlick DA. The impact of mental illness stigma on seeking and participating in mental health care. Psychol Sci Public Interest 2014;15:37–70. 10.1177/1529100614531398 [ PubMed : 26171956 ] [ CrossRef ] 173. Huggett C, Birtel M, Awenat Y, Fleming P, Wilkes S, Williams S, Haddock G. A qualitative study: experiences of stigma by people with mental health problems. Psychol Psychother 2018;91:380–97. [ PubMed : 29345416 ] 174. Lakeman R, Fitzgerald M. Ethical suicide research: a survey of researchers. Int J Ment Health Nurs 2009;18:10–17. 10.1111/j.1447-0349.2008.00569.x [ PubMed : 19125782 ] [ CrossRef ] 175. Berry K, Gregg L, Hartwell R, Haddock G, Fitzsimmons M, Barrowclough C. Therapist–client relationships in a psychological therapy trial for psychosis and substance misuse. Drug Alcohol Depend 2015;152:170–6. 10.1016/j.drugalcdep.2015.04.006 [ PubMed : 25962788 ] [ CrossRef ] 176. Awenat Y, Peters S, Gooding P, Pratt D, Shaw-Núñez E, Harris K, Haddock G. A qualitative analysis of suicidal psychiatric inpatients views and expectations of psychological therapy to counter suicidal thoughts, acts and deaths. BMC Psychiatry 2018;18. 10.1186/s12888-018-1921-6 [ PMC free article : PMC6192165 ] [ PubMed : 30326878 ] [ CrossRef ] 177. Blanchard M, Farber BA. ‘It is never okay to talk about suicide’: patients’ reasons for concealing suicidal ideation in psychotherapy. Psychother Res 2020;30:124–36. 10.1080/10503307.2018.1543977 [ PubMed : 30409079 ] [ CrossRef ] 178. Switzer F, Harper SF. A narrative review of the barriers to the implementation of cognitive behavioural therapy for psychosis. Psychosis 2019;11:151–61. 10.1080/17522439.2019.1578400 [ CrossRef ] 179. NICE. Surveillance Report 2017 – Psychosis and Schizophrenia in Adults: Prevention and Management (2014) NICE Guideline CG178. 9th November 2017. London, UK: NICE; 2017. [ PubMed : 31869041 ] 180. Barrowclough C, Meier P, Beardmore R, Emsley R. Predicting therapeutic alliance in clients with psychosis and substance misuse. J Nerv Ment Dis 2010;198:373–7. 10.1097/NMD.0b013e3181da4d4e [ PubMed : 20458201 ] [ CrossRef ] 181. Shattock L, Berry K, Degnan A, Edge D. Therapeutic alliance in psychological therapy for people with schizophrenia and related psychoses: a systematic review. Clin Psychol Psychother 2018;25:e60–85. 10.1002/cpp.2135 [ PubMed : 28961352 ] [ CrossRef ] 182. Huggett C, Peters S, Gooding P, Berry N, Pratt D. A systematic review and meta-ethnography of client and therapist perspectives of the therapeutic alliance in the context of psychotherapy and suicidal experiences. Clin Psychol Rev 2024;113:102469. [ PubMed : 39098267 ] 183. Awenat YF, Peters S, Gooding PA, Pratt D, Huggett C, Harris K, et al. Qualitative analysis of ward staff experiences during research of a novel suicide-prevention psychological therapy for psychiatric inpatients: understanding the barriers and facilitators. PLOS ONE 2019;14:e0222482. 10.1371/journal.pone.0222482 [ PMC free article : PMC6759174 ] [ PubMed : 31550251 ] [ CrossRef ] 184. Berry K, Haddock G. The implementation of the NICE guidelines for schizophrenia: Barriers to the implementation of psychological interventions and recommendations for the future. Psychol Psychother 2008;81:419–36. 10.1348/147608308x329540 [ PubMed : 18652741 ] [ CrossRef ] 185. Cranwell K, Polacsek M, McCann TV. Improving mental health service users’ with medical co-morbidity transition between tertiary medical hospital and primary care services: a qualitative study. BMC Health Serv Res 2016;16:302. 10.1186/s12913-016-1567-3 [ PMC free article : PMC4960840 ] [ PubMed : 27456864 ] [ CrossRef ] 186. Ellis LA, Churruca K, Braithwaite J. Mental health services conceptualised as complex adaptive systems: what can be learned? Int J Ment Health Syst 2017;11:43. 10.1186/s13033-017-0150-6 [ PMC free article : PMC5492119 ] [ PubMed : 28670339 ] [ CrossRef ] 187. Haldane V, Chuah FLH, Srivastava A, Singh SR, Koh GCH, Seng CK, Legido-Quigley H. Community participation in health services development, implementation, and evaluation: a systematic review of empowerment, health, community, and process outcomes. PLOS ONE 2019;14:e0216112. 10.1371/journal.pone.0216112 [ PMC free article : PMC6510456 ] [ PubMed : 31075120 ] [ CrossRef ] 188. Tindall RM, Ferris M, Townsend M, Boschert G, Moylan S. A first-hand experience of co-design in mental health service design: opportunities, challenges, and lessons. Int J Ment Health Nurs 2021;30:1693–702. 10.1111/inm.12925 [ PubMed : 34390117 ] [ CrossRef ] 189. Marshall P, Jones S, Gooding P, Robinson H, Lobban F. Caring for a family member with psychosis or bipolar disorder who has experienced suicidal behaviour: an exploratory qualitative study of an online peer-support forum. Int J Environ Res Public Health 2022;19:15192. 10.3390/ijerph192215192 [ PMC free article : PMC9690796 ] [ PubMed : 36429907 ] [ CrossRef ] 190. Chalkidou K, Tunis S, Whicher D, Fowler R, Zwarenstein M. The role for pragmatic randomized controlled trials (pRCTs) in comparative effectiveness research. Clin Trials 2012;9:436–46. 10.1177/1740774512450097 [ PubMed : 22752634 ] [ CrossRef ] 191. Hawton K, Casanas I Comabella C, Haw C, Saunders K. Risk factors for suicide in individuals with depression: A systematic review. J Affect Disord 2013;147:17–28. 10.1016/j.jad.2013.01.004 [ PubMed : 23411024 ] [ CrossRef ] 192. Kontaxakis V, Havaki-Kontaxaki B, Margariti M, Stamouli S, Kollias C, Christodoulou G. Suicidal ideation in inpatients with acute schizophrenia. Can J Psychiatry 2004;49:476–9. [ PubMed : 15362252 ] 193. Appleby L. Suicide in psychiatric-patients – risk and prevention. Br J Psychiatry 1992;161:749–58. [ PubMed : 1483160 ] 194. Appleby L, Hunt IM, Kapur N. New policy and evidence on suicide prevention. Lancet Psychiatry 2017;4:658–60. 10.1016/s2215-0366(17)30238-9 [ PubMed : 28549674 ] [ CrossRef ] 195. Bansal N, Karlsen S, Sashidharan SP, Cohen R, Chew-Graham CA, Malpass A. Understanding ethnic inequalities in mental healthcare in the UK: a meta-ethnography. PLOS Med 2022;19:e1004139. 10.1371/journal.pmed.1004139 [ PMC free article : PMC9746991 ] [ PubMed : 36512523 ] [ CrossRef ] 196. van den Berg AC, Giest SN, Groeneveld SM, Kraaij W. Inclusivity in online platforms: recruitment strategies for improving participation of diverse sociodemographic groups. Public Adm Rev 2020;80:989–1000. 10.1111/puar.13215 [ CrossRef ] 197. Wickham S, Taylor P, Shevlin M, Bentall RP. The impact of social deprivation on paranoia, hallucinations, mania and depression: the role of discrimination social support, stress and trust. PLOS ONE 2014;9:e105140. 10.1371/journal.pone.0105140 [ PMC free article : PMC4146475 ] [ PubMed : 25162703 ] [ CrossRef ] 198. Yur’yev A, Varnik P, Sisask M, Leppik L, Lumiste K, Värnik A. Some aspects of social exclusion: do they influence suicide mortality? Int J Soc Psychiatry 2013;59:232–8. 10.1177/0020764011431792 [ PubMed : 22205377 ] [ CrossRef ] 199. Chandler A. Socioeconomic inequalities of suicide: sociological and psychological intersections. Eur J Soc Theory 2020;23:33–51. 10.1177/1368431018804154 [ CrossRef ] 200. Simon GE, Yarborough BJ, Rossom RC, Lawrence JM, Lynch FL, Waitzfelder BE, et al. Self-reported suicidal ideation as a predictor of suicidal behavior among outpatients with diagnoses of psychotic disorders. Psychiatr Serv 2019;70:176–83. 10.1176/appi.ps.201800381 [ PMC free article : PMC6520048 ] [ PubMed : 30526341 ] [ CrossRef ] 201. Wyder M, De Leo D. Behind impulsive suicide attempts: indications from a community study. J Affect Disord 2007;104:167–73. 10.1016/j.jad.2007.02.015 [ PubMed : 17397934 ] [ CrossRef ] 202. Bentum JSV, Sijbrandij M, Huibers MJH, Huisman A, Arntz A, Holmes E, Kerkhof A. Treatment of intrusive suicidal imagery using eye movements. Int J Environ Res Public Health 2017;14:714. 10.3390/ijerph14070714 [ PMC free article : PMC5551152 ] [ PubMed : 28665329 ] [ CrossRef ] 203. Zortea TC, Cleare S, Melson AJ, Wetherall K, O'Connor RC. Understanding and managing suicide risk. Br Med Bull 2020;134:73–84. 10.1093/bmb/ldaa013 [ PubMed : 32435794 ] [ CrossRef ] 204. Belsher BE, Smolenski DJ, Pruitt LD, Bush NE, Beech EH, Workman DE, et al. Prediction models for suicide attempts and deaths: a systematic review and simulation. JAMA Psychiatry 2019;76:642–51. 10.1001/jamapsychiatry.2019.0174 [ PubMed : 30865249 ] [ CrossRef ] 205. Bull C, Byrnes J, Hettiarachchi R, Downes M. A systematic review of the validity and reliability of patient-reported experience measures. Health Serv Res 2019;54:1023–35. 10.1111/1475-6773.13187 [ PMC free article : PMC6736915 ] [ PubMed : 31218671 ] [ CrossRef ] 206. Fernandes S, Fond G, Zendjidjian XY, Baumstarck K, Lançon C, Berna F, et al.; French PREMIUM Group. Measuring the patient experience of mental health care: a systematic and critical review of patient-reported experience measures. Patient Prefer Adherence 2020;14:2147–61. 10.2147/ppa.S255264 [ PMC free article : PMC7653683 ] [ PubMed : 33192054 ] [ CrossRef ] 207. Barr PJ, Scholl I, Bravo P, Faber MJ, Elwyn G, McAllister M. Assessment of patient empowerment - a systematic review of measures. PLOS ONE 2015;10:e0126553. 10.1371/journal.pone.0126553 [ PMC free article : PMC4430483 ] [ PubMed : 25970618 ] [ CrossRef ] 208. Levac L, Ronis S, Cowper-Smith Y, Vaccarino O. A scoping review: the utility of participatory research approaches in psychology. J Community Psychol 2019;47:1865–92. 10.1002/jcop.22231 [ PMC free article : PMC6852237 ] [ PubMed : 31441516 ] [ CrossRef ] 209. Baines R, Donovan J, de Bere SR, Archer J, Jones R. Patient and public involvement in the design, administration and evaluation of patient feedback tools, an example in psychiatry: a systematic review and critical interpretative synthesis. J Health Serv Res Policy 2019;24:130–42. 10.1177/1355819618811866 [ PubMed : 30477354 ] [ CrossRef ] 210. van Ballegooijen W, Littlewood D, Nielsen E, Kapur N, Gooding P. The temporal relationships between defeat, entrapment and suicidal ideation: an ecological momentary assessment study. BJPsych Open 2022;8:e105. 10.1192/bjo.2022.68 [ PMC free article : PMC9230440 ] [ PubMed : 35656578 ] [ CrossRef ] 211. Kyle SD, Mulligan L, Emsley R, Neil ST, Kyle SD. High-resolution examination of the relationship between sleep disturbance, functioning and psychotic symptom severity in schizophrenia: a novel experience sampling study. J Sleep Res 2016;25:373–373. [ PubMed : 27362488 ] 212. Beautrais AL. Intervening to prevent suicide. Lancet Psychiatry 2014;1:165–7. 10.1016/S2215-0366(14)70304-9 [ PubMed : 26360713 ] [ CrossRef ] 213. Lalani M, Baines R, Bryce M, Marshall M, Mead S, Barasi S, et al. Patient and public involvement in medical performance processes: a systematic review. Health Expect 2019;22:149–61. 10.1111/hex.12852 [ PMC free article : PMC6433319 ] [ PubMed : 30548359 ] [ CrossRef ] 214. Teodorowski P, Rodgers SE, Fleming K, Tahir N, Ahmed S, Frith L. ‘To me, it’s ones and zeros, but in reality that one is death’: a qualitative study exploring researchers’ experience of involving and engaging seldom-heard communities in big data research. Health Expect 2023;26:882–91. 10.1111/hex.13713 [ PMC free article : PMC10010102 ] [ PubMed : 36691930 ] [ CrossRef ] 215. Crocker JC, Ricci-Cabello I, Parker A, Hirst JA, Chant A, Petit-Zeman S, et al. Impact of patient and public involvement on enrolment and retention in clinical trials: systematic review and meta-analysis. BMJ 2018;363:k4738. 10.1136/bmj.k4738 [ PMC free article : PMC6259046 ] [ PubMed : 30487232 ] [ CrossRef ] 216. Rose D, Rose N. Is ‘another’ psychiatry possible? Psychol Med 2023;53:46–54. 10.1017/S003329172200383X [ PubMed : 36628566 ] [ CrossRef ] 217. Rose D. The contemporary state of service-user-led research. Lancet Psychiatry 2015;2:959–60. 10.1016/s2215-0366(15)00435-6 [ PubMed : 26544740 ] [ CrossRef ] 218. Rose D. Participatory research: real or imagined. Soc Psychiatry Psychiatr Epidemiol 2018;53:765–71. 10.1007/s00127-018-1549-3 [ PMC free article : PMC6061456 ] [ PubMed : 29931442 ] [ CrossRef ] 219. Amico KR. Percent total attrition: a poor metric for study rigor in hosted intervention designs. Am J Public Health 2009;99:1567–75. 10.2105/ajph.2008.134767 [ PMC free article : PMC2724469 ] [ PubMed : 19608965 ] [ CrossRef ] 220. Dumville JC, Torgerson DJ, Hewitt CE. Reporting attrition in randomised controlled trials. BMJ 2006;332:969–71. 10.1136/bmj.332.7547.969 [ PMC free article : PMC1444839 ] [ PubMed : 16627519 ] [ CrossRef ] 221. Biggs K, Hind D, Gossage-Worrall R, Sprange K, White D, Wright J, et al. Challenges in the design, planning and implementation of trials evaluating group interventions. Trials 2020;21:116. 10.1186/s13063-019-3807-4 [ PMC free article : PMC6990578 ] [ PubMed : 31996259 ] [ CrossRef ] 222. O’Cathain A, Murphy E, Nicholl J. Three techniques for integrating data in mixed methods studies. BMJ 2010;341:c4587. 10.1136/bmj.c4587 [ PubMed : 20851841 ] [ CrossRef ] 223. Noyes J, Booth A, Moore G, Flemming K, Tunçalp O, Shakibazadeh E. Synthesising quantitative and qualitative evidence to inform guidelines on complex interventions: clarifying the purposes, designs and outlining some methods. BMJ Global Health 2019;4:e000893. 10.1136/bmjgh-2018-000893 [ PMC free article : PMC6350750 ] [ PubMed : 30775016 ] [ CrossRef ] 224. Tong FZY, Lederman R, D’Alfonso S, Berry K, Bucci S. Conceptualizing the digital therapeutic alliance in the context of fully automated mental health apps: a thematic analysis. Clin Psychol Psychother 2023;30:998–1012. 10.1002/cpp.2851 [ PubMed : 37042076 ] [ CrossRef ] 225. Bourke E, Barker C, Fornells-Ambrojo M. Systematic review and meta-analysis of therapeutic alliance, engagement, and outcome in psychological therapies for psychosis. Psychol Psychother 2021;94:822–53. 10.1111/papt.12330 [ PubMed : 33569885 ] [ CrossRef ] 226. Pawson R, Tilley N. An Introduction to Scientific Realist Evaluation. In Chelimsky E, Shadish WR, editors. Evaluation for the 21st Century: A Handbook. Thousand Oaks, CA: SAGE Publications Ltd; 1997. pp. 405–18. 227. Palm R, Hochmuth A. What works, for whom and under what circumstances? Using realist methodology to evaluate complex interventions in nursing: a scoping review. Int J Nurs Stud 2020;109:103601. 10.1016/j.ijnurstu.2020.103601 [ PubMed : 32590248 ] [ CrossRef ] 228. Rogers L, De Brún A, McAuliffe E. Defining and assessing context in healthcare implementation studies: a systematic review. BMC Health Serv Res 2020;20:591. 10.1186/s12913-020-05212-7 [ PMC free article : PMC7322847 ] [ PubMed : 32600396 ] [ CrossRef ] 229. Wong G, Westhorp G, Greenhalgh J, Manzano A, Jagosh J, Greenhalgh T. Quality and Reporting Standards, Resources, Training Materials and Information for Realist Evaluation: The RAMESES II Project. Southampton (UK): NIHR Journals Library; 2017. [ PubMed : 29072890 ] 230. Lobban F, Coole M, Donaldson E, Glossop Z, Haines J, Johnston R, et al. Improving Peer Online Forums (iPOF): protocol for a realist evaluation of peer online mental health forums to inform practice and policy. BMJ Open 2023;13:e075142. 10.1136/bmjopen-2023-075142 [ PMC free article : PMC10387651 ] [ PubMed : 37518092 ] [ CrossRef ] 231. Gooding PA, Harris K, Haddock G. Psychological resilience to suicidal experiences in people with non-affective psychosis: a position paper. Int J Environ Res Public Health 2022;19:3813. 10.3390/ijerph19073813 [ PMC free article : PMC8997645 ] [ PubMed : 35409502 ] [ CrossRef ] 232. Harris K, Haddock G, Peters S, Gooding P. Psychological resilience to suicidal thoughts and behaviours in people with schizophrenia diagnoses: a systematic literature review. Psychol Psychother 2020;93:777–809. 10.1111/papt.12255 [ PubMed : 31625283 ] [ CrossRef ] 233. Huggett C, Gooding P, Haddock G, Pratt D. The relationship between the therapeutic alliance and suicidal experiences in people with psychosis receiving therapy. Int J Environ Res Public Health 2021;18:10706. 10.3390/ijerph182010706 [ PMC free article : PMC8535896 ] [ PubMed : 34682451 ] [ CrossRef ] 234. Huggett C, Gooding P, Haddock G, Quigley J, Pratt D. The relationship between the therapeutic alliance in psychotherapy and suicidal experiences: a systematic review. Clin Psychol Psychother 2022;29:1203–35. 10.1002/cpp.2726 [ PMC free article : PMC9546023 ] [ PubMed : 35168297 ] [ CrossRef ] 235. Peters S, Awenat Y, Gooding PA, Harris K, Cook L, Huggett C, et al. What is important to service users and staff when implementing suicide-focused psychological therapies for people with psychosis into mental health services? Front Psychiatry 2023;14:1154092. 10.3389/fpsyt.2023.1154092 [ PMC free article : PMC10213358 ] [ PubMed : 37252139 ] [ CrossRef ] Copyright © 2026 Gooding et al . This work was produced by Gooding et al . under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This is an Open Access publication distributed under the terms of the Creative Commons Attribution CC BY 4.0 licence, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. See: https://creativecommons.org/licenses/by/4.0/ . For attribution the title, original author(s), the publication source – NIHR Journals Library, and the DOI of the publication must be cited. Bookshelf ID: NBK621216 Contents < Prev Next > Share Views PubReader Print View Cite this Page Gooding P, Awenat Y, Drake R, et al. A psychological talking therapy for suicidality in people experiencing non-affective psychosis: Mechanism and efficacy outcomes of the CARMS (Cognitive AppRoaches to coMbatting Suicidality) randomised controlled trial. Southampton (UK): National Institute for Health and Care Research; 2026 Mar. (Efficacy and Mechanism Evaluation, No. 13.03.) References. 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