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Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells

Samuele Ferrari et al.
HAL (France) · Papers · License: Open Access
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crispr
CRISPR-Cas9 DNA damage response DNA double-strand breaks adeno-associated vector gene editing genotoxicity hematopoietic stem/progenitor cells integrase-defective lentiviral vector inverted terminal repeats p53 pathway, 0
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