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In silico screening of 15 polyphenols and reference compounds against MMP-1 + SIRT1 for topical photoaging: real Boltz-2 data positions EMB-3 at the top of the panel; Resveratrol leads SIRT1 axis; classical references (vitamin C, niacinamide, ferulic acid) rank low
in silico, drug discovery, pharmacology, skin aging, egcg
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