Skip to main Communities My dashboard Log in Sign up Published April 18, 2026 | Version v1 Dataset Open HOW STRESS AFFECTS HUMAN HEALTH Authors/Creators Karlibaeva Ulbosin Jangabay kizi (Contact person) 1 Orazbaev Nuraliy Amanaliyevich (Contact person) 2 Nortojiyev Muhammad Anvar ugli (Contact person) 3 Show affiliations 1.
215-"A" group ,The Second Faculty of General Medicine 2.
The Second Faculty of General Medicine 116-"B"group 3.
Tashkent State Medical University Teacher Description This article comprehensively analyzes the phenomenon of stress, which is one of the most pressing problems of modern psychology and physiology. In the research, along with the traditional classification of stress — acute, episodic, and chronic types — the negative consequences of hypostress (lack of stress), a condition that has been little studied but is dangerous for human life, are thoroughly explained. Based on the Yerkes–Dodson law, the importance of the “golden mean” necessary for human efficiency and the concept of beneficial stress (eustress) are revealed. In the central part of the article, the biochemical mechanisms of stress are analyzed, in particular the activity of the hypothalamus–pituitary–adrenal axis (HPA axis) and the effects of the hormones cortisol and adrenaline on the organism. Additionally, age-related characteristics of stress — toxic stress in childhood, emotional instability in adolescence, and occupational “burnout” in adults — are compared, and strategies for activating natural antidotes such as oxytocin, endorphin, and serotonin hormones are recommended. Files 824-826.pdf Files (209.3 kB) Name Size Download all 824-826.pdf md5:fdd9b5a44b30fc437e4813e825655adf 209.3 kB Preview Download Additional details References Selye, H. (1950). The Physiology and Pathology of Exposure to Stress. Montreal: Acta Inc. Yerkes, R. M., & Dodson, J. D. (1908). The relation of strength of stimulus to rapidity of habit-formation. Journal of Comparative Neurology and Psychology, 18(5), 459–482. McEwen, B. S. (2007). Physiology and neurobiology of stress and adaptation: Central role of the brain. Physiological Reviews, 87(3), 873–904. Sapolsy, R. M. (2004). Why Zebras Don't Get Ulcers: The Acclaimed Guide to Stress, Stress-Related Diseases, and Coping. Holt Paperbacks. Shonkoff, J. P., & Garner, A. S. (2012). The lifelong effects of early childhood adversity and toxic stress. Pediatrics, 129(1), e232–e246. 25 Views 28 Downloads Show more details All versions This version Views Total views 25 25 Downloads Total downloads 28 28 Data volume Total data volume 5.9 MB 5.9 MB More info on how stats are collected.... Versions External resources Indexed in OpenAIRE Communities Details DOI DOI Badge DOI 10.5281/zenodo.19644077 Markdown [](https://doi.org/10.5281/zenodo.19644077) reStructuredText .. image:: https://zenodo.org/badge/DOI/10.5281/zenodo.19644077.svg :target: https://doi.org/10.5281/zenodo.19644077 HTML <a href="https://doi.org/10.5281/zenodo.19644077"><img src="https://zenodo.org/badge/DOI/10.5281/zenodo.19644077.svg" alt="DOI"></a> Image URL https://zenodo.org/badge/DOI/10.5281/zenodo.19644077.svg Target URL https://doi.org/10.5281/zenodo.19644077 Resource type Dataset Publisher Zenodo Published in The Journalof Applied Science and Social Science, 16(04), 824-826, ISSN: 2229-3205, 2026. Rights License Creative Commons Attribution 4.0 International The Creative Commons Attribution license allows re-distribution and re-use of a licensed work on the condition that the creator is appropriately credited. Read more Citation Export Technical metadata Created April 18, 2026 Modified April 18, 2026 Jump up About About Policies Infrastructure Principles Projects Roadmap Contact Blog Blog Support Help FAQ Developers REST API OAI-PMH Contribute GitHub Donate Funded by Powered by CERN Data Centre & InvenioRDM Status Privacy policy Cookie policy Terms of Use This site uses cookies. Find out more on how we use cookies Accept all cookies Accept only essential cookies