Insight Into the Epigenetics of Alzheimer's Disease: A computational study from Human Interactome

Skip to main Communities My dashboard Log in Sign up Published July 13, 2025 | Version v1 Journal article Open Insight Into the Epigenetics of Alzheimer's Disease: A computational study from Human Interactome Authors/Creators Dhalvinder Raj 1 Dr. Manish Kumar 2 Show affiliations 1.

Research Scholar, P.K. University, Shivpuri, Madhya Pradesh, India 2.

Professor, P.K. University, Shivpuri, Madhya Pradesh, India Description The elderly are disproportionately affected by these diseases. An example of this is In the United States, the sixth leading cause of death in adults is Alzheimer's disease (AD). To identify miR biomarkers in PD, we used transcriptomic and text mining approaches as part of a computational systems biology investigation of the disease. In order to understand the recurring pattern of regulation peculiar to AD, several network motifs were examined, including Feed Forward Loops (FFLs), Feed Back Loops (FBLs), and Multiple Input Modules (MIMs). Additionally, the study examined this network motif's epigenetic regulation in connection to miR-related lncRNAs, histone modification pattern, and DNA islands inside the miR promoter region. The function of these authorities in Alzheimer's disease was further reinforced by the results of the tissue specificity study. Files 4-2-5.1.pdf Files (583.3 kB) Name Size Download all 4-2-5.1.pdf md5:fcd4abcdcc9b2210cc9f2877f4d1f999 583.3 kB Preview Download Additional details Software Repository URL https://researchtrendsjournal.com/article/642/insight-into-the-epigenetics-of-alzheimer's-disease-a-computational-study-from-human-interactome 19 Views 163 Downloads Show more details All versions This version Views Total views 19 19 Downloads Total downloads 163 163 Data volume Total data volume 96.8 MB 96.8 MB More info on how stats are collected.... Versions External resources Indexed in OpenAIRE Communities Keywords and subjects Keywords Alzheimer's disease, Feed Forward Loops, DNA, Multiple Input Modules Details DOI DOI Badge DOI 10.5281/zenodo.18937220 Markdown [](https://doi.org/10.5281/zenodo.18937220) reStructuredText .. image:: https://zenodo.org/badge/DOI/10.5281/zenodo.18937220.svg :target: https://doi.org/10.5281/zenodo.18937220 HTML <a href="https://doi.org/10.5281/zenodo.18937220"><img src="https://zenodo.org/badge/DOI/10.5281/zenodo.18937220.svg" alt="DOI"></a> Image URL https://zenodo.org/badge/DOI/10.5281/zenodo.18937220.svg Target URL https://doi.org/10.5281/zenodo.18937220 Resource type Journal article Publisher International Journal of Trends in Emerging Research and Development Published in International Journal of Trends in Emerging Research and Development, 3(4), 232-239, ISSN: 2584-282X, 2025. Languages English Rights License Creative Commons Attribution 4.0 International The Creative Commons Attribution license allows re-distribution and re-use of a licensed work on the condition that the creator is appropriately credited. Read more Citation Export Technical metadata Created April 14, 2026 Modified April 14, 2026 Jump up About About Policies Infrastructure Principles Projects Roadmap Contact Blog Blog Support Help FAQ Developers REST API OAI-PMH Contribute GitHub Donate Funded by Powered by CERN Data Centre & InvenioRDM Status Privacy policy Cookie policy Terms of Use This site uses cookies. Find out more on how we use cookies Accept all cookies Accept only essential cookies

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