Epigenetic Modulation and Digital Environments: A Structural Model of Sense Formation

This article proposes a theoretical framework for understanding how digital environments and artificial intelligence modulate cognitive life prior to the formation of meaning. It introduces the concept of the pre-semantic threshold, defined as the level where sense emerges as a form of the possible before stabilizing into representations. Through the processes of activation, inhibition, and resonance, algorithmic architectures do not merely transmit data: they orient perceptual postures and cognitive predispositions. Conceptual epigenetics is presented as a transdisciplinary heuristic model that describes the environmental modulation of sense, situating itself within the tradition of the philosophy of technology (McLuhan, Simondon, Kittler), the philosophy of information (Floridi), and enactive cognitive science (Varela, Thompson, Gallagher). The essay demonstrates a formal homology between the plasticity of memory studied by Ramirez and algorithmic modulation, clarifying that these are selective processes operating on distinct ontological planes. Finally, the clinical implications for AI psychiatry are discussed, with concrete examples of pathological resonance in contemporary digital ecosystems.