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Reproducibility of 3D chromatin configuration reconstructions

Segal, Mark R et al.
eScholarship · Papers
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49-mathematical-sciences-for-2020models
It is widely recognized that the three-dimensional (3D) architecture of eukaryotic chromatin plays an important role in processes such as gene regulation and cancer-driving gene fusions. Observing or inferring this 3D structure at even modest resolutions had been problematic, since genomes are highl
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