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How muscle talks to brain: apelin protein mediates exercise-induced antidepressant effects

Yu J et al.
Europe PMC · Papers
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biomedicallife-science
Physical exercise alleviates depressive symptoms and enhances hippocampal plasticity, but the mediators of muscle-brain crosstalk underlying these effects are not fully understood. We evaluated apelin as a novel mediator of the antidepressant effects of physical exercise, specifically testing the hy
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