Europe PMC
open access
Homozygous CHD8 mutation intensifies ASD phenotypes and attenuates sex differences
CHD8 is a chromatin remodeler implicated in autism spectrum disorders (ASD) and multiple neurodevelopmental disorders, yet heterozygous Chd8-mutant mouse lines often exhibit only mild ASD-related phenotypes, leaving its role unclear. Because a complete knockout of Chd8 causes embryonic lethality, we
Conceptio Open Archive
Analyze & explore related research in Conceptio
Connect this record directly into your research workflow or AI agent. Explore citations across open repositories, query full text, and export structured proof bundles.
This document is indexed with metadata only: full text is not available in the archive for this record. Open the official source ↗
Related documents
- DCPS modulates TDP-43-linked neurodegeneration through P-body-mediated RNA decay#261809
- miR-708-5p is elevated in bipolar patients and can induce mood disorder-associated behavior in mice#312007
- miR-181a-5p: a key regulator of placental function in health and disease#642661
- Evidence for sexual antagonism and antagonistic pleiotropy in the maintenance of late onset Alzheimer’s disease alleles#424606
- Editorial: Circuits plasticity in neurodegenerative disorders: targeting mood disorders#1166247
Record · ID 784427
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Bring this data into your agent: Connect via MCP or API · 20 free credits to start · no card required
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive