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Configurational diversity of metabotropic glutamate receptor complexes with beta-arrestins

Marx DC et al.
Europe PMC · Papers
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biomedicallife-science
Beta-arrestins (β-arrs) are cytosolic proteins which mediate G protein-coupled receptor (GPCR) desensitization, endocytosis, and signaling. Despite the widespread physiological roles of β-arr coupling, the molecular basis of GPCR/β-arr interaction has been studied primarily in monomeric family A GPC
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