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Are infraslow oscillations the missing link between sleep and Alzheimer's?

Grollero D et al.
Europe PMC · Papers
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alzheimer-s-diseaseglymphatic-system
Introduction Locus coeruleus (LC) and glymphatic dysfunction have been linked both to Alzheimer's disease (AD) and, recently, to infraslow oscillation (ISO) in sleep spindle (sigma) activity (ISO). Here we hypothesize ISO integrity is a critical link between sleep and AD. Methods We a
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