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Dengue virus envelope epitope-specific antibodies are associated with protection from severe dengue

Lay S et al.
Europe PMC · Papers
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biomedicallife-science
Our understanding of a protective humoral immune response to dengue virus (DENV) remains limited. The envelope (E) protein is the main antibody (Ab) target. While anti-fusion loop (FL) epitope monoclonal Abs (mAbs) can induce antibody dependent enhancement (ADE) in vitro, some mAbs targeting quatern
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