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Enantioselective Synthesis of Atropisomeric 3,3′-Biindoles via Three-Component de Novo Indolization
biochemistrybiotechnologycomputational-biologymicrobiologymolecular-biologypharmacologyplant-biologysociology
The catalytic atroposelective synthesis of 3,3′-biindoles remains a formidable challenge due to the inherent configurational lability of the [5–5] heterobiaryl system. Herein, we report a three-component de novo indolization from simple α-keto aldehydes, 2-substituted indoles, and 2-na
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