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Deficiency of Gankyrin in the small intestine is associated with augmented colitis accompanied by altered bacterial composition of intestinal microbiota

Sakurai, Toshiharu et al.
Kyoto University Research Information Repository · Papers
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inflammatory-bowel-diseasemicrobiota
Background: Gankyrin (GK) is an oncoprotein which regulates inflammatory responses and its inhibition is considered as a possible anti-inflammatory therapy for inflammatory bowel disease (IBD). Methods: In this study, we investigated the role of GK in epithelial cells using mice with intestinal epit
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