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Decoding gene regulatory networks from single-cell RNA velocity

Meng, Lingqi et al.
arXiv (All) · Papers
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34a5562j07dynamical-systemsoptimization-and-control
We formulate gene regulatory network reconstruction from RNA velocity as a sparse dynamical inverse problem. We show that control-only data can be structurally nonidentifying and characterize excitation conditions under which controlled perturbations restore identifiability by generating complementa
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