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Ultraviolet Exposure, Antioxidant Use and Skin Erythema at Extreme High Altitude

Sunnybrook Health Sciences Centre · 2007
ClinicalTrials.gov · Datasets · License: Public Domain · 2007
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altitudeantioxidantsoxidative-stress
With the increasing tourism and adventure travel into extreme environments comes the need to reassess the required protection against ultraviolet (UV) radiation and possible other oxidative stresses. This is an observational study of UV radiation exposure and skin erythema while at extreme altitude (Mt. Everest). In addition to UV exposure, skin erythema, antioxidant use (such as vitamins C and E) will be measured. Hypothesis: 1. UV radiation at extreme altitude has larger effects on the skin than at sea level; therefore requiring an adjustment of the antioxidant use for adequate protection. 2. The skin is an accurate reflection of UV and oxidative stress exposure 3. The efficacy of oxidatives stress is reflective of the ethnicity of the individual.
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