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Vitamin D Status and Immune-inflammatory Status in Different UK Populations With COVID-19 Infection

Guy's and St Thomas' NHS Foundation Trust · 2020
ClinicalTrials.gov · Datasets · License: Public Domain · 2020
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covid19cytokinesethnicityvitamin-d
Hypothesis: Serum Vitamin D (25(OH)D) is significantly lower in severe versus non-severe COVID-19 infections and that this is a function of ethnicity. There is an association between vitamin D status and various cytokines (pro-inflammatory molecules). The primary objective of this research is to provide a snap shot of vitamin D status in patients from the South-East London area by age, sex, ethnicity and BMI and demonstrate ethnic differences in vitamin D status as well as its associations with severe vs non-severe COVID-19 infections. The secondary objective is to determine if there is an association between vitamin D status and various cytokines (pro-inflammatory molecules) and severity of disease.
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