Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders

invasive prenatal diagnosis in a context of family history of single-gene disorders, including, sickle cell disease, cystic fibrosis, fragile x syndrome, proximal spinal muscular atrophy, myotonic dystrophy, muscular dystrophy, duchenne, muscular dystrophy, becker, neurofibromatosis-noonan syndrome, huntington disease, hemophilia a, hemophilia b