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HepB mAb19 in Individuals With Chronic Hepatitis B Infection

Rockefeller University · 2023
ClinicalTrials.gov · Datasets · License: Public Domain · 2023
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hepatitis-bhepatitis-b-virusmonoclonal-antibody
This is a first-in-human, placebo-controlled, single dose, dose-escalation phase 1 study to evaluate the safety, pharmacokinetics and antiviral activity of a highly potent neutralizing anti-HBV monoclonal antibody (mAb), HepB mAb19, which targets the S-protein in individuals with chronic hepatitis B (CHB) on nucleos(t)ide analog therapy (NRTI).
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