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Cerebrovascular Reactivity in Hepatic Encephalopathy

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran · 2010
ClinicalTrials.gov · Datasets · License: Public Domain · 2010
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liver-cirrhosis
It has been observed that patients with cirrhosis present a generalized state of vasoconstriction as an homeostatic response to splanchnic arteriolar vasodilatation. On progression of the disease, vascular regulation is mismatched, causing altered systemic blood flow and lose in the cerebrovascular reactivity. The investigators hypothesize that the altered cerebrovascular reactivity induces neurological disturbances related to hepatic encephalopathy and, therefore, the existence of a correlation between cerebrovascular reactivity and the stage of hepatic encephalopathy.
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