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Crosstalk between cytokines and IgG N-Glycosylation: Bidirectional effects and relevance to clinical innovation for inflammatory diseases

Chen, Zhixian et al.
Research Online · Papers
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cytokinesdiseasesimmunoglobulin-ginflammationmedicine-and-health-sciences
The crosstalk between cytokines and immunoglobulin G (IgG) N-glycosylation forms a bidirectional regulatory network that significantly impacts inflammation and immune function. This review examines how various cytokines, both pro- and anti-inflammatory, modulate IgG N-glycosylation, shaping antibody
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