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Investigating the roles of human RNaseH2 in response to oncogene- and chemotherapy-induced replication stress

Wilkins, Rosanna Jade
UBIRA ETheses · Papers
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q-science-general
RNaseH2 is a nuclear endoribonuclease that has essential roles in maintaining genome integrity in eukaryotes by degrading the RNA moiety of RNA:DNA hybrids and removing single genome-embedded ribonucleotides to prevent DNA replication stress. RNaseH2 is a heterotrimeric complex that requires all thr
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