Nutritional Therapy of the Deficits of Oxidation Mitochondrial of the Fatty Acids

Usual dietary therapies of mitochondrial fatty acid oxidation disorders (FAO) are based on 3 strategies: * limitation of lipid intake in the diet; * supplementation of the diet with medium-chain triglycerides (MCT) for patients affected with disorders of long-chain FAO; * some specific supplementations (for example, L-carnitine). These strategies are often ineffective. The aim of the present study is to evaluate new therapeutic ways based on the underlying energetic defect observed in these disorders. The long-term goal is to develop efficient therapies of these disorders.