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Reducing Hemodialysis Induced Recurrent Brain Injury to Improve Patients' Lives

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · 2018
ClinicalTrials.gov · Datasets · License: Public Domain · 2018
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chronic-kidney-diseasedialysishemodialysisna
Patients who receive dialysis for kidney failure suffer severe cognitive impairment. Hemodialysis causes circulatory stress and ischemia, which causes severe brain injury. It has been demonstrated that a procedure known as Remote Ischemic Preconditioning(RIPC), which involves wrapping a blood pressure cuff around a patient's leg and inflating has the potential of protecting many organs, such as the heart from the effects of dialysis. Our study aims to investigate this phenomenon to determine the extent to which it provides protection to a dialysis patient's brain.
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