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Study of Applications of Autologous Epidermal Cells in Liquid Phase in the Treatment of Vitiligo

Centre Hospitalier Universitaire de Nice · 2011
ClinicalTrials.gov · Datasets · License: Public Domain · 2011
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Vitiligo is a depigmenting skin disease common. Vitiligo is caused by the disappearance of melanocytes in the epidermis. Vitiligo is the cause of disfigurement, psychological and social, that sounds a lot about the quality of life. Currently the standard treatment for vitiligo is ultraviolet ray (UV), but it only allows a 50% repigmentation of lesions in half of patients. The applications of autologous epidermal cells in the liquid phase is a promising new therapeutic approach of vitiligo. The main goal of this study is to compare prospectively the repigmentation of vitiligo lesions induced by application of autologous epidermal cells in liquid phase associated with light therapy and light therapy alone. Study's secondary goals: compare the applications of epidermal cells to phototherapy alone and phototherapy, in respect of: * Obtain a repigmentation\> 70% (threshold considered aesthetically relevant) * The occurrence of adverse events * Patient satisfaction regarding the efficacy and safety of treatment
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