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PK of Piperacillin/Tazobactam in Adults Undergoing ECMO

Columbia University · 2019
ClinicalTrials.gov · Datasets · License: Public Domain · 2019
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antimicrobials
This study is designed to provide preliminary data to determine if concentrations of piperacillin/tazobactam change in patients with severe respiratory failure receiving extracorporeal membrane oxygenation (ECMO). The investigators hypothesize that patients will have significant changes in concentration measurements, specifically an increased clearance rate and increased volume of distribution, during ECMO as compared to critically ill patients.
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