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The Expression Heparanase in Term and Preterm Placentas

Hillel Yaffe Medical Center · 2019
ClinicalTrials.gov · Datasets · License: Public Domain · 2019
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preterm-birth
Heparanase is an endo-β-glucuronidase that cleaves heparin-sulfate (HS) side chains of heparan sulfate proteoglycans, an integral constituent of the extra cellular matrix (ECM). This study aims to investigate the association between heparanase expression in the human placenta and preterm birth (PTB) . The investigators hypothesize that an abnormal placentation causes relative placental ischemia that induces higher rates of heparanase expression.
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