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Neurofilament Light Chain And Voice Acoustic Analyses In Dementia Diagnosis

Monash University · 2021
ClinicalTrials.gov · Datasets · License: Public Domain · 2021
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alzheimer-s-diseasebiomarkerdementianeurodegenerationneurodegenerative-diseasesspeech
This cohort study aims to determine if a blood test can aid with diagnosing dementia in anyone presenting with cognitive complaints to a single healthcare network. The investigators will measure levels of a brain protein, Neurofilament light chain (Nfl), and assess changes in language using speech tests. Participants will have a single blood test and speech test, and will be followed up at 12-months to complete questionnaires and cognitive scales over the phone. The speech test will also be completed again at 12-months. Individuals at risk of a Fronto-temporal dementia syndrome will be eligible to complete optional genetic testing involving an 'at home' saliva sample.
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